18690563. Prodrugs of Antibiotic Teixobactin (The Regents of the University of California)
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Prodrugs of Antibiotic Teixobactin
Organization Name
The Regents of the University of California
Inventor(s)
Chelsea R. Jones of Irvine CA (US)
James S. Nowick of Irvine CA (US)
Prodrugs of Antibiotic Teixobactin
This abstract first appeared for US patent application 18690563 titled 'Prodrugs of Antibiotic Teixobactin
Original Abstract Submitted
Prodrugs of antibiotic teixobactin, methods of their synthesis, and methods of their use as antimicrobial treatments are described. The teixobactin prodrugs incorporate one or more O-acyl linkages. The O-acyl linkages can be utilized in substitution of amide peptide bonds between an amino acid containing an alcohol side chain and the immediately preceding amino acid.
