18674511. METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION simplified abstract (Boston Scientific Scimed, Inc.)

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METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION

Organization Name

Boston Scientific Scimed, Inc.

Inventor(s)

Steven R. Mickelsen of Iowa City IA (US)

METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION - A simplified explanation of the abstract

This abstract first appeared for US patent application 18674511 titled 'METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION

Simplified Explanation:

This patent application discloses catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation.

  • An apparatus includes a voltage pulse generator and an electrode controller.
  • The voltage pulse generator produces a pulsed voltage waveform.
  • The electrode controller is operably coupled to the voltage pulse generator and a medical device with electrodes.
  • The electrode controller includes a selection module and a pulse delivery module.
  • The selection module selects a subset of electrodes, identifying anodes and cathodes.
  • The pulse delivery module delivers the pulsed voltage waveform to the subset of electrodes.

Key Features and Innovation:

  • Selective and rapid application of DC voltage for irreversible electroporation.
  • Voltage pulse generator produces a pulsed voltage waveform.
  • Electrode controller selects electrodes and delivers voltage to drive electroporation.

Potential Applications:

  • Medical procedures requiring irreversible electroporation for tissue ablation.
  • Cancer treatment through targeted cell destruction.

Problems Solved:

  • Efficient and controlled application of DC voltage for electroporation.
  • Selective targeting of specific cells or tissues for treatment.

Benefits:

  • Precise and effective treatment with minimal damage to surrounding tissues.
  • Improved outcomes in medical procedures requiring electroporation.

Commercial Applications:

  • Medical device companies for developing advanced catheter systems.
  • Hospitals and healthcare facilities for cancer treatment and tissue ablation procedures.

Prior Art:

Prior research on electroporation techniques and devices in the medical field.

Frequently Updated Research:

Ongoing studies on the application of electroporation in various medical treatments.

Questions about Electroporation Technology:

1. How does the selective application of DC voltage improve the efficiency of irreversible electroporation? 2. What are the potential long-term effects of using electroporation for tissue ablation in medical procedures?


Original Abstract Submitted

Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

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