18667993. FLOW CELLS simplified abstract (ILLUMINA, INC.)

FLOW CELLS

Organization Name

ILLUMINA, INC.

Inventor(s)

Jeffrey S. Fisher of San Diego CA (US)

Brian D. Mather of San Diego CA (US)

Maria Candelaria Rogert Bacigalupo of Encinitas CA (US)

Justin Fullerton of San Diego CA (US)

Ludovic Vincent of San Diego CA (US)

Lewis J. Kraft of San Diego CA (US)

Sahngki Hong of San Diego CA (US)

Boyan Boyanov of San Diego CA (US)

M. Shane Bowen of Encinitas CA (US)

Sang Park of San Diego CA (US)

Wayne N. George of Ilford (GB)

Andrew A. Brown of Cambridge (GB)

Dajun Yuan of San Diego CA (US)

FLOW CELLS - A simplified explanation of the abstract

This abstract first appeared for US patent application 18667993 titled 'FLOW CELLS

The abstract of the patent application describes a flow cell that includes a substrate with two sets of primers attached to different regions. One set includes an un-cleavable first primer and a cleavable second primer, while the other set includes a cleavable first primer and an un-cleavable second primer.

• The flow cell design includes two sets of primers with different cleavability properties.
• The first primer set consists of an un-cleavable first primer and a cleavable second primer.
• The second primer set comprises a cleavable first primer and an un-cleavable second primer.
• This design allows for controlled cleavage of primers during the flow cell process.
• The flow cell configuration enhances the efficiency and accuracy of sequencing reactions.

Potential Applications:

• Next-generation sequencing technologies
• Molecular biology research
• Diagnostic testing in healthcare

Problems Solved:

• Improves the accuracy of sequencing reactions
• Enhances the efficiency of flow cell processes

Benefits:

• Increased precision in sequencing results
• Streamlined workflow in molecular biology research
• Potential for faster and more cost-effective diagnostic testing

Commercial Applications:

• Biotechnology companies for research and development
• Healthcare industry for diagnostic applications

Questions about the technology: 1. How does the design of the flow cell improve sequencing accuracy? 2. What are the potential cost savings associated with this technology?

Frequently Updated Research: Stay updated on advancements in flow cell technology for sequencing applications.

Original Abstract Submitted

An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.