18666005. MODULATING VENULENESS OF ENDOTHELIAL CELLS (President and Fellows of Harvard College)
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MODULATING VENULENESS OF ENDOTHELIAL CELLS
Organization Name
President and Fellows of Harvard College
Inventor(s)
UIrich H. Von Andrian of Chestnut Hill MA (US)
Aude Thiriot of Brookline MA (US)
Kristin Rattay of Cambridge MA (US)
Munir M. Mosaheb of Sharon MA (US)
MODULATING VENULENESS OF ENDOTHELIAL CELLS
This abstract first appeared for US patent application 18666005 titled 'MODULATING VENULENESS OF ENDOTHELIAL CELLS
Original Abstract Submitted
Disclosed herein are genes which are differentially expressed in venule endothelial cells (V-ECs) compared to non-venule endothelial cells (NV-ECs), and methods and compositions relating to those genes. In particular, described herein are methods of reducing the venuleness of endothelial cells (ECs) for treating inflammatory diseases, and methods of increasing the venuleness of ECs for treating cancers.
