18605551. METHOD OF EVALUATING IMMUNE RESPONSE OF CELL GROUP TO TEST SUBSTANCE simplified abstract (CANON KABUSHIKI KAISHA)

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METHOD OF EVALUATING IMMUNE RESPONSE OF CELL GROUP TO TEST SUBSTANCE

Organization Name

CANON KABUSHIKI KAISHA

Inventor(s)

KOUICHI Kato of Kanagawa (JP)

TAKANORI Yoda of Kyoto (JP)

TSUTOMU Honma of Tokyo (JP)

METHOD OF EVALUATING IMMUNE RESPONSE OF CELL GROUP TO TEST SUBSTANCE - A simplified explanation of the abstract

This abstract first appeared for US patent application 18605551 titled 'METHOD OF EVALUATING IMMUNE RESPONSE OF CELL GROUP TO TEST SUBSTANCE

The method described in the abstract involves evaluating the immune response of a cell group to a test substance by immobilizing a cell membrane modifier on a substrate, introducing a calcium fluorescent indicator into the cell group, adding the test substance, and detecting the fluorescence of the cell group with a detector.

  • Immobilizing a cell membrane modifier on a substrate
  • Introducing a calcium fluorescent indicator into the cell group
  • Adding a test substance to the cell group
  • Detecting the fluorescence of the cell group with a detector

Potential Applications: - Research in immunology and cell biology - Drug development and testing - Understanding immune responses to various substances

Problems Solved: - Provides a method to evaluate immune responses in a controlled environment - Allows for precise measurement of cellular reactions to test substances

Benefits: - Accurate assessment of immune responses - Potential for identifying new drug candidates - Enhances understanding of cellular behavior

Commercial Applications: Title: Immune Response Evaluation Method This technology could be used in pharmaceutical research, biotechnology companies, and academic research institutions to study immune responses and develop new drugs.

Questions about the technology: 1. How does this method improve upon existing techniques for evaluating immune responses? 2. What are the potential limitations of using a calcium fluorescent indicator in this context?

Frequently Updated Research: Stay updated on the latest advancements in immunology and cell biology research to enhance the understanding and application of this technology.


Original Abstract Submitted

Provided is a method of evaluating the immune response of a cell group to a test substance, the method comprising the steps of: immobilizing a cell membrane modifier comprising a polymer having a hydrophobic chain and a hydrophilic chain on a substrate; introducing a calcium fluorescent indicator into the cell group; immobilizing the cell group on the substrate through the cell membrane modifier, adding the test substance to the cell group; and detecting the fluorescence of the cell group derived from the calcium fluorescent indicator with a detector.