18564478. MASSIVE GENERATION OF CHEMICALLY LIGATEABLE PROBES FOR MULTIPLEXED FISH simplified abstract (California Institute of Technology)

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MASSIVE GENERATION OF CHEMICALLY LIGATEABLE PROBES FOR MULTIPLEXED FISH

Organization Name

California Institute of Technology

Inventor(s)

Long Cai of Pasadena CA (US)

Chee Huat (Linus) Eng of Pasadena CA (US)

MASSIVE GENERATION OF CHEMICALLY LIGATEABLE PROBES FOR MULTIPLEXED FISH - A simplified explanation of the abstract

This abstract first appeared for US patent application 18564478 titled 'MASSIVE GENERATION OF CHEMICALLY LIGATEABLE PROBES FOR MULTIPLEXED FISH

Simplified Explanation:

This patent application describes methods for creating a large number of chemically ligateable probes for multiplexed Fluorescence In Situ Hybridization (FISH) using a hybrid-primer.

Key Features and Innovation:

  • Generation of a massive number of chemically ligateable probes for FISH.
  • Utilization of a hybrid-primer for probe creation.
  • Solving problems in the field of multiplexed FISH.

Potential Applications: The technology can be used in genetic research, medical diagnostics, and biotechnology for studying gene expression and chromosomal abnormalities.

Problems Solved: The technology addresses the need for a high number of probes for multiplexed FISH, as well as streamlining the probe creation process.

Benefits:

  • Increased efficiency in probe generation.
  • Enhanced capabilities for multiplexed FISH experiments.
  • Improved accuracy in genetic analysis.

Commercial Applications: The technology has potential commercial applications in research institutions, diagnostic laboratories, and biotechnology companies for genetic analysis and diagnostics.

Questions about the Technology: 1. How does this technology improve the efficiency of FISH experiments? 2. What are the potential limitations of using a hybrid-primer for probe generation?

Frequently Updated Research: Stay updated on the latest advancements in multiplexed FISH techniques and probe generation methods to enhance the application of this technology.


Original Abstract Submitted

Disclosed herein are methods for generating a massive number of chemically ligateable probes for multiplexed Fluorescence In Situ Hybridization (FISH) using a hybrid-primer. Also, the disclosure sets forth methods, in addition to using the same, and other solutions to problems in the relevant field.