18555167. Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device simplified abstract (Robert Bosch GmbH)
Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device
Organization Name
Inventor(s)
Franz Laermer of Weil Der Stadt (DE)
Michael Dreschmann of Muenchen (DE)
Jochen Hoffmann of Renningen (DE)
Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device - A simplified explanation of the abstract
This abstract first appeared for US patent application 18555167 titled 'Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device
The abstract describes a method for trapping nucleated cells using electrodes in a microfluidic device.
- The method involves applying a sample liquid containing nucleated cells to a carrier substrate.
- A current signal is provided to the electrodes to generate an electric field in a microcavity, trapping the nucleated cells as target cells.
Potential Applications:
- Cell sorting and isolation in biological research.
- Medical diagnostics for detecting rare cells in blood samples.
Problems Solved:
- Efficient trapping and manipulation of nucleated cells in a microfluidic system.
- Precise control over cell positioning for analysis and experimentation.
Benefits:
- Increased accuracy and speed in cell trapping processes.
- Reduction in manual labor and potential for automation in cell analysis.
Commercial Applications:
- Biotechnology companies for cell analysis and sorting devices.
- Medical research institutions for diagnostic tools.
Questions about the technology: 1. How does this method compare to traditional cell trapping techniques? 2. What are the potential limitations of using electrodes for cell trapping in a microfluidic device?
Frequently Updated Research: Ongoing studies focus on optimizing the electrode design for enhanced cell trapping efficiency and exploring new applications for the technology.
Original Abstract Submitted
A method for trapping at least one nucleated cell using at least one electrode for a microfluidic device is disclosed. The method includes (i) outputting an application signal that causes a sample liquid comprising the at least one nucleated cell to be applied to a carrier substrate of the microfluidic device, and (ii) providing a current signal to an interface with the at least one electrode in order to generate, at or in a microcavity of the carrier substrate, an electric field configured to trap the at least one nucleated cell as a target cell in the microcavity.
