18544247. GENE THERAPY TREATMENT OF ATRIAL FIBRILLATION simplified abstract (NORTHWESTERN UNIVERSITY)
Contents
GENE THERAPY TREATMENT OF ATRIAL FIBRILLATION
Organization Name
Inventor(s)
Rishi Arora of Chicago IL (US)
GENE THERAPY TREATMENT OF ATRIAL FIBRILLATION - A simplified explanation of the abstract
This abstract first appeared for US patent application 18544247 titled 'GENE THERAPY TREATMENT OF ATRIAL FIBRILLATION
Abstract: Compositions, methods, and devices for the treatment and prevention of atrial fibrillation (AF) using gene therapy techniques are disclosed. Inhibiting oxidative stress (OS) and parasympathetic nervous system signaling can prevent and/or reverse the electrical remodeling underlying AF.
- Simplified Explanation:
- The patent application discusses using gene therapy techniques to treat and prevent atrial fibrillation by inhibiting oxidative stress and parasympathetic nervous system signaling.
- Key Features and Innovation:
- Utilizes gene therapy techniques for AF treatment. - Targets oxidative stress and parasympathetic nervous system signaling. - Aims to prevent and reverse electrical remodeling in AF.
- Potential Applications:
- Treatment and prevention of atrial fibrillation. - Gene therapy for cardiac arrhythmias.
- Problems Solved:
- Addressing the underlying causes of atrial fibrillation. - Preventing electrical remodeling in the heart.
- Benefits:
- Improved treatment options for AF. - Potential reversal of electrical remodeling. - Targeted therapy for specific mechanisms of AF.
- Commercial Applications:
- Title: Gene Therapy for Atrial Fibrillation Treatment. - Potential commercial uses in the pharmaceutical industry. - Market implications for cardiac arrhythmia treatments.
- Questions about Gene Therapy for Atrial Fibrillation Treatment:
1. How does gene therapy target oxidative stress in atrial fibrillation? - Gene therapy can deliver genetic material to inhibit oxidative stress pathways in the heart.
2. What are the implications of inhibiting parasympathetic nervous system signaling in AF treatment? - Inhibiting parasympathetic signaling can help regulate heart rhythm and prevent arrhythmias.
Original Abstract Submitted
Provided herein are compositions, methods, and devices for the treatment and prevention of atrial fibrillation (AF) using gene therapy techniques. In particular, oxidative stress (OS) and parasympathetic nervous system signaling are inhibited to prevent and/or reverse the electrical remodeling that underlies AF.
