18542511. FLOW CELLS simplified abstract (ILLUMINA, INC.)

FLOW CELLS

Organization Name

ILLUMINA, INC.

Inventor(s)

Gianluca Andrea Artioli of Cambridge (GB)

Johan Sebastian Basuki of Singapore (SG)

Boyan Boyanov of San Diego CA (US)

Gabriele Canzi of San Diego CA (US)

Sahngki Hong of San Diego CA (US)

Nam Nguyen of Cambridge (GB)

Sebastien Georg Gabriel Ricoult of Cambridge (GB)

Alexandra Szemjonov of Cambridge (GB)

Xavier Von Hatten of Cambridge (GB)

FLOW CELLS - A simplified explanation of the abstract

This abstract first appeared for US patent application 18542511 titled 'FLOW CELLS

The abstract describes a flow cell with a substrate, reactive regions separated across the substrate, and removable coatings over each reactive region, including gas-dissolvable coatings.

• The flow cell includes a substrate with spatially separated reactive regions.
• Each reactive region has a polymeric hydrogel layer and a reactive entity attached to it.
• Removable coatings are positioned over each reactive region, with at least one being a gas-dissolvable coating.

Potential Applications: - Biomedical research for drug delivery systems - Environmental monitoring for gas detection - Industrial processes for chemical reactions

Problems Solved: - Facilitates controlled reactions in specific regions - Enables easy removal and replacement of coatings - Enhances efficiency and precision in chemical processes

Benefits: - Improved accuracy in targeted reactions - Simplified maintenance and cleaning process - Versatile applications in various industries

Commercial Applications: Title: "Innovative Flow Cell Technology for Enhanced Chemical Reactions" This technology can be utilized in pharmaceutical research, environmental monitoring, and industrial manufacturing processes to optimize reactions and improve overall efficiency.

Questions about Flow Cell Technology: 1. How does the gas-dissolvable coating enhance the functionality of the flow cell?

  - The gas-dissolvable coating allows for controlled release of gases, facilitating specific reactions in the flow cell.

2. What are the advantages of using a polymeric hydrogel layer in each reactive region?

  - The polymeric hydrogel layer provides a stable and flexible platform for attaching reactive entities, ensuring precise and reliable reactions.

Original Abstract Submitted

An example of a flow cell includes a substrate; a plurality of reactive regions spatially separated from one another across the substrate; and a plurality of independently removable coatings respectively positioned over each of the plurality of reactive regions. Each of the plurality of reactive regions includes a polymeric hydrogel layer; and a reactive entity attached to the polymeric hydrogel layer. At least one of the independently removable coatings is a gas-dissolvable coating.