18468102. LIPID COMPOSITION AND SUBSTANCE DELIVERY METHOD simplified abstract (KABUSHIKI KAISHA TOSHIBA)

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LIPID COMPOSITION AND SUBSTANCE DELIVERY METHOD

Organization Name

KABUSHIKI KAISHA TOSHIBA

Inventor(s)

Emi Nozaki of Shinagawa (JP)

Eiichi Akahoshi of Shinagawa (JP)

Mitsuko Ishihara of Setagaya (JP)

LIPID COMPOSITION AND SUBSTANCE DELIVERY METHOD - A simplified explanation of the abstract

This abstract first appeared for US patent application 18468102 titled 'LIPID COMPOSITION AND SUBSTANCE DELIVERY METHOD

The patent application describes a lipid composition designed to deliver an objective substance to a target cell under specific conditions.

  • The composition includes a substance delivery carrier with lipid particles encapsulating the objective substance.
  • The lipid particles are liposomes containing FFT-10 and/or FFT-20 as constituents.
  • The target cell is exposed to the composition at a temperature of 37°C or higher.

Potential Applications:

  • Drug delivery systems for targeted therapy.
  • Gene therapy applications for specific cell types.
  • Research tools for studying cellular uptake mechanisms.

Problems Solved:

  • Efficient delivery of substances to target cells.
  • Enhanced stability and protection of encapsulated substances.
  • Controlled release of substances at specific temperatures.

Benefits:

  • Increased efficacy of drug delivery.
  • Reduced off-target effects.
  • Improved cellular uptake of therapeutic agents.

Commercial Applications:

  • Pharmaceutical companies for developing targeted therapies.
  • Biotechnology firms for gene therapy research.
  • Research institutions for studying cellular interactions.

Questions about the Technology: 1. How does the lipid composition improve the delivery of substances to target cells? 2. What are the potential limitations of using FFT-10 and FFT-20 in lipid particles for encapsulation?

Frequently Updated Research: Ongoing studies may focus on optimizing the lipid composition for different types of objective substances and target cells, as well as exploring additional constituents for improved delivery efficiency.


Original Abstract Submitted

According to one embodiment, a lipid composition is for delivering an objective substance to a target cell. The composition is contacted with the target cell under an environment of 37° C. or higher. The composition includes a substance delivery carrier having lipid particle and an objective substance encapsulated in the lipid particle. The lipid particle constitutes a liposome and includes FFT-10 and/or FFT-20 as constituents thereof.

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