18439987. PRODUCTION OF RETINOL simplified abstract (DSM IP ASSETS B.V.)

PRODUCTION OF RETINOL

Organization Name

DSM IP ASSETS B.V.

Inventor(s)

Nathalie Balch of Kaiseraugst (CH)

Paul Blomquist of Kaiseraugst (CH)

Reed Doten of Kaiseraugst (CH)

Peter Houston of Kaiseraugst (CH)

Ethan Lam of Kaiseraugst (CH)

Jenna Mcmahon of Kaiseraugst (CH)

Joshua Trueheart of Kaiseraugst (CH)

Celine Viarouge of Kaiseraugst (CH)

PRODUCTION OF RETINOL - A simplified explanation of the abstract

This abstract first appeared for US patent application 18439987 titled 'PRODUCTION OF RETINOL

The present invention involves a new enzymatic process for producing vitamin A alcohol (retinol) from retinal, using heterologous enzymes with retinal reductase activity to achieve at least 90% conversion efficiency.

• Enzymatic process for converting retinal to retinol
• Use of heterologous enzymes with retinal reductase activity
• Achieves at least 90% conversion efficiency
• Particularly useful for biotechnological production of vitamin A
• Novel approach to vitamin A production

Potential Applications: - Biotechnological production of vitamin A - Pharmaceutical industry for vitamin A supplements - Nutraceuticals for dietary supplements

Problems Solved: - Efficient conversion of retinal to retinol - Cost-effective production of vitamin A - Sustainable and environmentally friendly process

Benefits: - High conversion efficiency - Reduced production costs - Increased availability of vitamin A supplements

Commercial Applications: Title: Enzymatic Process for Vitamin A Production: Commercial Uses and Market Implications Description: This technology can be utilized in pharmaceutical and nutraceutical industries for the production of vitamin A supplements, potentially leading to cost savings and increased availability in the market.

Questions about Enzymatic Process for Vitamin A Production: 1. How does this enzymatic process compare to traditional methods of producing vitamin A? - The enzymatic process offers higher conversion efficiency and potentially lower production costs compared to traditional methods. 2. What are the potential environmental benefits of using this enzymatic process for vitamin A production? - The enzymatic process may be more sustainable and environmentally friendly compared to chemical synthesis methods.

Original Abstract Submitted

The present invention is related to a novel enzymatic process for production of vitamin A alcohol (retinol) via conversion of retinal, which process includes the use of heterologous enzymes having activity as retinal reductase, particularly wherein the reaction leads to at least about 90% conversion of retinal into retinol. Said process is particularly useful for biotechnological production of vitamin A.