18392429. NANOPORE SENSING DEVICE WITH MULTIPLE SENSING LAYERS simplified abstract (IMEC VZW)
Contents
NANOPORE SENSING DEVICE WITH MULTIPLE SENSING LAYERS
Organization Name
Inventor(s)
Anne Verhulst of Houtvenne (BE)
Pol Van Dorpe of Spalbeek (BE)
Cedric Huyghebaert of Heverlee (BE)
NANOPORE SENSING DEVICE WITH MULTIPLE SENSING LAYERS - A simplified explanation of the abstract
This abstract first appeared for US patent application 18392429 titled 'NANOPORE SENSING DEVICE WITH MULTIPLE SENSING LAYERS
The abstract describes a nanopore sensing device with multiple sensors for detecting an electric feature in the nanopore, including field-effect transistors.
- Nanopore sensing device with a nanopore containing multiple sensors for electric feature detection
- Each sensor is part of a sensing layer, with isolating layers separating adjacent pairs of sensing layers
- At least one sensor is a field-effect transistor
- Sensors are arranged along the length of the nanopore
Potential Applications: - DNA sequencing - Protein analysis - Drug delivery monitoring
Problems Solved: - Enhanced sensitivity in detecting electric features in nanopores - Improved accuracy in analyzing biomolecules
Benefits: - Higher precision in molecular analysis - Real-time monitoring capabilities - Potential for miniaturization and portability
Commercial Applications: Title: "Advanced Nanopore Sensing Devices for Biomedical Applications" This technology could be used in medical diagnostics, pharmaceutical research, and biotechnology industries, leading to more efficient and accurate analysis of biomolecules.
Questions about Nanopore Sensing Devices: 1. How do nanopore sensing devices compare to traditional methods of biomolecule analysis?
- Nanopore sensing devices offer real-time monitoring and higher sensitivity compared to traditional methods.
2. What are the potential challenges in commercializing this technology for widespread use?
- Challenges may include scaling up production, ensuring reliability, and regulatory approval processes.
Original Abstract Submitted
In a first aspect, a nanopore sensing device is provided that includes: (i) a nanopore having a first orifice and second orifice, and a length running from the first to the second orifice; and (ii) one or more sensors for sensing an electric feature in the nanopore; wherein the nanopore sensing device comprises a plurality of sensing layers arranged along the length, each sensing layer being part of one of the sensors and each adjacent pair of sensing layers being separated by an isolating layer, and at least one of the sensors is a field-effect transistor.
