18343768. Structured Nucleic Acid Templated Architectures simplified abstract (Massachusetts Institute of Technology)
Contents
Structured Nucleic Acid Templated Architectures
Organization Name
Massachusetts Institute of Technology
Inventor(s)
Nayan Agarwal of Cambridge MA (US)
Ashwin Gopinath of Cambridge MA (US)
Structured Nucleic Acid Templated Architectures - A simplified explanation of the abstract
This abstract first appeared for US patent application 18343768 titled 'Structured Nucleic Acid Templated Architectures
The patent application describes inorganic nucleic acid supramolecular structures and methods for creating them.
- Structured nucleic acid polymer micelle with a nucleic acid template, functional moieties, and interacting polymers.
- Inorganic shell surrounding the nucleic acid template, maintaining functionality of the moieties.
- The functional moieties extend outside the micelle and shell.
Potential Applications: - Drug delivery systems - Biomedical imaging - Nanotechnology
Problems Solved: - Enhancing stability of nucleic acid structures - Improving targeted drug delivery
Benefits: - Increased efficiency in drug delivery - Enhanced structural stability of nucleic acids
Commercial Applications: Title: "Inorganic Nucleic Acid Supramolecular Structures: Commercial Applications and Market Implications" Description: Potential uses in pharmaceuticals, biotechnology, and materials science industries.
Questions about Inorganic Nucleic Acid Supramolecular Structures: 1. How do inorganic nucleic acid supramolecular structures differ from traditional drug delivery systems? - Inorganic nucleic acid supramolecular structures offer enhanced stability and functionality compared to traditional systems. 2. What are the key advantages of using inorganic shells in nucleic acid structures? - Inorganic shells provide protection and structural support to the nucleic acid templates, improving overall functionality.
Original Abstract Submitted
Provided herein are inorganic nucleic acid supramolecular structures and methods for making them. In certain aspects, the construct includes a structured nucleic acid polymer micelle, which micelle includes a structured nucleic acid template; one or more functional moieties attached to the template; and polymers that interact with nucleic acid present in the template to form the structured nucleic acid polymer micelle; and an inorganic shell surrounding the structured nucleic acid template, in which the one or more functional moieties extend outside the structured nucleic acid polymer micelle and the inorganic shell to maintain functionality.
