18302738. METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY simplified abstract (The Regents of the University of California)

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METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY

Organization Name

The Regents of the University of California

Inventor(s)

Daniel K. Nomura of Walnut Creek CA (US)

Roberto Zoncu of San Francisco CA (US)

Carl Ward of Berkeley CA (US)

Sin Ki Fung of Berkeley CA (US)

Chris Kumar Varma of Portola Valley CA (US)

Benjamin Fontaine of Berkeley CA (US)

METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY - A simplified explanation of the abstract

This abstract first appeared for US patent application 18302738 titled 'METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY

Simplified Explanation

The patent application discusses methods and compounds for targeted autophagy.

  • Targeted autophagy is a process that involves the selective degradation of specific cellular components.
  • The methods and compounds described in the patent application aim to enhance the efficiency and specificity of targeted autophagy.
  • These innovations could potentially lead to advancements in the treatment of various diseases, including neurodegenerative disorders and cancer.
  • By targeting specific cellular components for degradation, these methods and compounds may help to remove damaged or harmful structures within cells.

Potential Applications

The technology described in the patent application could have the following potential applications:

  • Treatment of neurodegenerative disorders
  • Cancer therapy
  • Cellular rejuvenation research

Problems Solved

The technology addresses the following problems:

  • Lack of specificity in autophagy processes
  • Inefficiency in targeting specific cellular components for degradation

Benefits

The technology offers the following benefits:

  • Enhanced efficiency in targeted autophagy
  • Selective removal of damaged or harmful cellular components
  • Potential for improved treatment outcomes in various diseases

Potential Commercial Applications

The technology could be applied in the following commercial settings:

  • Pharmaceutical companies developing new therapies
  • Biotechnology companies focused on cellular research

Possible Prior Art

One example of prior art in this field is the use of small molecules to modulate autophagy pathways. Researchers have explored various compounds that can enhance or inhibit autophagy for therapeutic purposes.

Unanswered Questions

How do these methods and compounds compare to existing autophagy modulation techniques?

The article does not provide a direct comparison to existing techniques for modulating autophagy pathways. Further research may be needed to determine the advantages of the methods and compounds described in the patent application.

What are the potential side effects or limitations of using targeted autophagy in therapeutic applications?

The article does not address potential side effects or limitations of targeted autophagy in therapeutic settings. Additional studies may be required to assess the safety and efficacy of these methods and compounds in clinical use.


Original Abstract Submitted

Provided herein, inter alia, are methods and compounds for targeted autophagy.