18196402. EXPANDED VACUUM-STABLE GELS FOR MULTIPLEXED HIGH RESOLUTION SPATIAL HISTOPATHOLOGY simplified abstract (The Board of Trustees of the Leland Stanford Junior University)
Contents
- 1 EXPANDED VACUUM-STABLE GELS FOR MULTIPLEXED HIGH RESOLUTION SPATIAL HISTOPATHOLOGY
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 EXPANDED VACUUM-STABLE GELS FOR MULTIPLEXED HIGH RESOLUTION SPATIAL HISTOPATHOLOGY - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Potential Applications
- 1.6 Problems Solved
- 1.7 Benefits
- 1.8 Potential Commercial Applications
- 1.9 Possible Prior Art
- 1.10 Original Abstract Submitted
EXPANDED VACUUM-STABLE GELS FOR MULTIPLEXED HIGH RESOLUTION SPATIAL HISTOPATHOLOGY
Organization Name
The Board of Trustees of the Leland Stanford Junior University
Inventor(s)
Garry P. Nolan of Redwood City CA (US)
Yunhao Bai of Stanford CA (US)
Bokai Zhu of Redwood City CA (US)
Xavier Rovira Clave of Redwood City CA (US)
Sizun Jiang of Redwood City CA (US)
EXPANDED VACUUM-STABLE GELS FOR MULTIPLEXED HIGH RESOLUTION SPATIAL HISTOPATHOLOGY - A simplified explanation of the abstract
This abstract first appeared for US patent application 18196402 titled 'EXPANDED VACUUM-STABLE GELS FOR MULTIPLEXED HIGH RESOLUTION SPATIAL HISTOPATHOLOGY
Simplified Explanation
The method described in the abstract involves processing a tissue sample using a negatively charged expandable gel. Here is a simplified explanation of the patent application:
- Permeating the tissue section with monomers for a negatively charged expandible gel
- Allowing the monomers to polymerize in the tissue sample
- Hydrating the tissue sample, causing it to expand
- Adhering the expanded tissue sample to a positively charged surface
- Dehydrating the expanded tissue sample while it is on the planar surface
Potential Applications
This technology could be used in various fields such as tissue engineering, regenerative medicine, and pathology for sample preparation and analysis.
Problems Solved
This method provides a way to efficiently process tissue samples for further analysis, allowing for better visualization and examination of the tissue structure.
Benefits
The benefits of this technology include improved sample preparation, enhanced tissue expansion for better analysis, and potential applications in various scientific and medical fields.
Potential Commercial Applications
Potential commercial applications of this technology could include use in research laboratories, pathology labs, and medical facilities for tissue sample processing and analysis.
Possible Prior Art
One possible prior art for this technology could be methods involving tissue expansion for sample preparation and analysis, but the specific use of a negatively charged expandable gel may be a novel aspect of this innovation.
Unanswered Questions
How does this method compare to traditional tissue processing techniques?
This article does not provide a direct comparison between this method and traditional tissue processing techniques. It would be interesting to know the advantages and disadvantages of this new method compared to existing practices.
What are the potential limitations or challenges of implementing this technology in real-world settings?
The article does not address any potential limitations or challenges that may arise when implementing this technology in practical applications. Understanding these factors could be crucial for successful adoption and integration of this method in various industries.
Original Abstract Submitted
Provided herein is a method for processing a tissue sample. The method may comprise: (a) permeating the tissue section with monomers for a negatively charged expandible gel, (b) allowing the monomers to polymerize in the tissue sample, (c) hydrating the tissue sample, thereby causing the sample to expand, (d) adhering expanded tissue sample to a positively charged surface and (e) dehydrating the expanded tissue sample while it is on the planar surface.
