18041902. EUKARYOTIC DNA REPLICATION ORIGINS, AND VECTOR CONTAINING THE SAME simplified abstract (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE)
Contents
- 1 EUKARYOTIC DNA REPLICATION ORIGINS, AND VECTOR CONTAINING THE SAME
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 EUKARYOTIC DNA REPLICATION ORIGINS, AND VECTOR CONTAINING THE SAME - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Potential Applications
- 1.6 Problems Solved
- 1.7 Benefits
- 1.8 Potential Commercial Applications
- 1.9 Possible Prior Art
- 1.10 How does this method compare to existing techniques for isolating DNA replication origins in mammalian cells?
- 1.11 What are the potential limitations or challenges of isolating and studying DNA replication origins using this method?
- 1.12 Original Abstract Submitted
EUKARYOTIC DNA REPLICATION ORIGINS, AND VECTOR CONTAINING THE SAME
Organization Name
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventor(s)
Marcel Mechali of Montferrier-sur-Lez (FR)
Ildem Akerman of Birmingham (GB)
Nadège Gaborit of Valflaunes (FR)
EUKARYOTIC DNA REPLICATION ORIGINS, AND VECTOR CONTAINING THE SAME - A simplified explanation of the abstract
This abstract first appeared for US patent application 18041902 titled 'EUKARYOTIC DNA REPLICATION ORIGINS, AND VECTOR CONTAINING THE SAME
Simplified Explanation
The method described in the abstract is for isolating a mammalian genomic DNA replication origin. Here is a simplified explanation of the patent application:
- Isolating genomic DNA molecules
- Identifying 500 bp windows within the DNA molecules
- Isolating fragments of 500 pb up to 6000 pb
- Selecting a DNA replication origin capable of producing nascent DNA and initiating DNA replication
- Isolating the selected origin
Potential Applications
This technology could be used in genetic research, DNA replication studies, and understanding the mechanisms of DNA replication in mammalian cells.
Problems Solved
This method solves the problem of isolating and identifying specific DNA replication origins in mammalian genomic DNA, which can be crucial for studying DNA replication processes.
Benefits
The benefits of this technology include a better understanding of DNA replication mechanisms, potential insights into genetic diseases related to DNA replication, and advancements in genetic engineering techniques.
Potential Commercial Applications
Potential commercial applications of this technology could include developing diagnostic tools for genetic diseases, creating new biotechnological products, and improving genetic engineering processes.
Possible Prior Art
One possible prior art in this field is a method for isolating DNA replication origins in bacterial genomes, which may have similarities but would not be directly applicable to mammalian genomic DNA replication origins.
Unanswered Questions
How does this method compare to existing techniques for isolating DNA replication origins in mammalian cells?
Answer: This article does not provide a direct comparison to existing techniques, leaving the reader to wonder about the advantages and limitations of this new method compared to established ones.
What are the potential limitations or challenges of isolating and studying DNA replication origins using this method?
Answer: The article does not address any potential limitations or challenges that researchers may face when applying this method, leaving room for uncertainty about its practicality and effectiveness in real-world applications.
Original Abstract Submitted
A method for isolating a mammalian genomic DNA replication origin, the method including: isolating the genomic DNA molecules; identifying 500 bp windows within the DNA molecules; isolating from the genomic DNA molecules the fragments that have a size from 500 pb up 6000 pb; selecting a DNA replication origin that is able, when contained in the DNA of an Eukaryotic cell, to produce nascent DNA, and to initiate DNA replication; and isolating the origin.
