17931277. SEQUENCE ALIGNMENT WITH MEMORY ARRAYS simplified abstract (Micron Technology, Inc.)

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SEQUENCE ALIGNMENT WITH MEMORY ARRAYS

Organization Name

Micron Technology, Inc.

Inventor(s)

Justin Eno of Boise ID (US)

Sean S. Eilert of Boise ID (US)

Ameen D. Akel of Boise ID (US)

Kenneth M. Curewitz of Boise ID (US)

SEQUENCE ALIGNMENT WITH MEMORY ARRAYS - A simplified explanation of the abstract

This abstract first appeared for US patent application 17931277 titled 'SEQUENCE ALIGNMENT WITH MEMORY ARRAYS

Simplified Explanation

A memory device is used to implement a Bloom filter by storing portions of a reference genetic sequence and comparing them to a read sequence through a multiply-accumulate operation.

  • Memory device implements a Bloom filter using a memory array.
  • Memory device stores portions of a reference genetic sequence.
  • Memory device compares portions of the reference genetic sequence to a read sequence in parallel.
  • Multiply-accumulate operation is performed to determine alignment of the read sequence to the reference sequence.

Potential Applications

This technology can be applied in:

  • Genomic sequencing
  • Bioinformatics
  • DNA analysis

Problems Solved

This technology helps in:

  • Efficient comparison of genetic sequences
  • Quick alignment of read sequences to reference sequences

Benefits

The benefits of this technology include:

  • Faster processing of genetic data
  • Improved accuracy in sequence alignment

Potential Commercial Applications

      1. Genomic Sequencing Advancements: How Memory Devices are Revolutionizing DNA Analysis ###
      1. Questions ###

How does this technology impact the field of bioinformatics?

This technology significantly improves the efficiency and accuracy of genetic sequence comparison and alignment, making it a valuable tool for bioinformatics researchers.

What are the potential limitations of using memory devices for implementing Bloom filters in genetic sequencing?

One potential limitation could be the complexity and cost of integrating memory devices into existing sequencing platforms. Additionally, the scalability of this technology for large-scale genomic studies may need further exploration.


Original Abstract Submitted

A memory device may be used to implement a Bloom filter. In some examples, the memory device may include a memory array to perform a multiply-accumulate operation to implement the Bloom filter. The memory device may store multiple portions of a reference genetic sequence in the memory array and compare the portions of the reference genetic sequence to a read sequence in parallel by performing the multiply-accumulate operation. The results of the multiply-accumulate operation between the read sequence and the portions of the reference genetic sequence may be used to determine where the read sequence aligns to the reference sequence.