18678144. METHODS FOR MEASURING AN AMOUNT OF AN ANALYTE IN A COMPLEX SAMPLE simplified abstract (Robert Bosch GmbH)
Contents
METHODS FOR MEASURING AN AMOUNT OF AN ANALYTE IN A COMPLEX SAMPLE
Organization Name
Inventor(s)
Nadezda Fomina of Redwood City CA (US)
Christopher Johnson of San Carlos CA (US)
Young Shik Shin of Mountain View CA (US)
Christoph Lang of Sunnyvale CA (US)
METHODS FOR MEASURING AN AMOUNT OF AN ANALYTE IN A COMPLEX SAMPLE - A simplified explanation of the abstract
This abstract first appeared for US patent application 18678144 titled 'METHODS FOR MEASURING AN AMOUNT OF AN ANALYTE IN A COMPLEX SAMPLE
The abstract describes a method for detecting the amount of an analyte in a solution using an assay chamber with an electrode and capture molecule.
- Assay chamber with an electrode and capture molecule
- Solution with analyte, binding partner, electrochemically active agent, and detecting probe
- Electrical signal changes pH near electrode
- Analyte binds to capture molecule and detecting probe
- Signal from signaling tag measured to calculate analyte amount
Potential Applications: - Medical diagnostics - Environmental monitoring - Food safety testing
Problems Solved: - Accurate and sensitive detection of analytes in solutions - Rapid and efficient analysis process
Benefits: - High sensitivity and specificity - Quick results - Cost-effective solution for analyte detection
Commercial Applications: Title: "Innovative Analyte Detection Method for Various Industries" This technology can be used in healthcare, environmental, and food industries for efficient and accurate analyte detection, leading to improved processes and outcomes.
Prior Art: Readers can start searching for prior art related to electrochemical detection methods, biosensors, and analyte quantification techniques.
Frequently Updated Research: Stay updated on advancements in electrochemical sensing, biosensor technologies, and analytical chemistry methods for continuous improvement in analyte detection techniques.
Questions about Analyte Detection Method: 1. How does the method compare to traditional analyte detection techniques? The method offers higher sensitivity and specificity compared to traditional techniques, leading to more accurate results. 2. What are the potential limitations of this method in real-world applications? Some potential limitations may include the need for specialized equipment and expertise for operation, as well as the cost of reagents and consumables.
Original Abstract Submitted
A method for detecting an amount of an analyte in a solution includes providing an assay chamber including an electrode positioned at a first end of the assay chamber and a capture molecule attached to the electrode via a linker. A solution including an analyte, a binding partner of the analyte, at least one electrochemically active agent, and a detecting probe having a signaling tag attached thereto may be provided to the assay chamber. An electrical signal may be applied to the electrode to change the pH of the solution in the area near the electrode. The analyte may bind to the capture molecule and to the detecting probe at the first end of the assay chamber at the new pH. A signal produced by the signaling tag at the first end of the assay chamber may be measured to calculate the amount of the analyte in the solution.
