18674492. METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION simplified abstract (Boston Scientific Scimed, Inc.)

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METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION

Organization Name

Boston Scientific Scimed, Inc.

Inventor(s)

Steven R. Mickelsen of Iowa City IA (US)

METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION - A simplified explanation of the abstract

This abstract first appeared for US patent application 18674492 titled 'METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION

Simplified Explanation: This patent application discloses catheter systems and methods for applying DC voltage to drive irreversible electroporation quickly and selectively.

  • An apparatus includes a voltage pulse generator and an electrode controller.
  • The voltage pulse generator produces a pulsed voltage waveform.
  • The electrode controller is coupled to the voltage pulse generator and a medical device with electrodes.
  • The electrode controller selects a subset of electrodes, designating some as anodes and others as cathodes.
  • A pulse delivery module delivers the pulsed voltage waveform to the selected electrodes.

Key Features and Innovation:

  • Catheter systems for selective and rapid application of DC voltage for irreversible electroporation.
  • Voltage pulse generator produces pulsed voltage waveform.
  • Electrode controller selects subset of electrodes and delivers voltage to them.
  • Enables precise targeting of specific tissue for electroporation.

Potential Applications:

  • Cancer treatment through irreversible electroporation.
  • Targeted cell ablation in medical procedures.
  • Research in gene therapy and cell biology.

Problems Solved:

  • Precise and targeted application of DC voltage for electroporation.
  • Efficient and controlled cell membrane permeabilization.
  • Minimizing damage to surrounding healthy tissue.

Benefits:

  • Enhanced precision in medical procedures.
  • Reduced side effects compared to traditional treatments.
  • Improved outcomes in cancer therapy.

Commercial Applications: Electroporation catheter systems for targeted cancer treatment and cell ablation procedures in medical settings.

Prior Art: Prior art related to this technology may include research on electroporation methods and devices in the medical field.

Frequently Updated Research: Ongoing research on improving the efficiency and safety of electroporation techniques for medical applications.

Questions about Catheter Systems for Irreversible Electroporation: 1. How does this technology improve the precision of electroporation in medical procedures? 2. What are the potential long-term implications of using this catheter system for cancer treatment?


Original Abstract Submitted

Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

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