18280158. Heteroaromatic Inhibitors of Cancer Metabolism simplified abstract (Vanderbilt University)

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Heteroaromatic Inhibitors of Cancer Metabolism

Organization Name

Vanderbilt University

Inventor(s)

H. Charles Manning of Franklin TN (US)

Heteroaromatic Inhibitors of Cancer Metabolism - A simplified explanation of the abstract

This abstract first appeared for US patent application 18280158 titled 'Heteroaromatic Inhibitors of Cancer Metabolism

Simplified Explanation

The present disclosure provides compounds useful as amino acid transporter inhibitors. Amino acid transporter inhibitors are useful to treat a variety of diseases, disorders, or conditions including cancer.

  • Amino acid transporter inhibitors are compounds that can block the transport of amino acids into cells.
  • These inhibitors can be used in the treatment of various diseases, including cancer, by disrupting the amino acid supply needed for cell growth and proliferation.
  • The compounds disclosed in the patent application have shown promise in inhibiting amino acid transport and may have potential therapeutic applications in cancer treatment.

Potential Applications

The potential applications of this technology include:

  • Treatment of cancer by inhibiting amino acid transport in cancer cells.
  • Development of new therapies for other diseases and disorders that rely on amino acid transport for cell growth.

Problems Solved

This technology helps address the following problems:

  • Providing a new approach to treating cancer by targeting amino acid transport.
  • Offering potential solutions for diseases and disorders that involve dysregulated amino acid transport.

Benefits

The benefits of this technology include:

  • Potential for more effective and targeted cancer treatments.
  • Possibility of developing novel therapies for a range of diseases by targeting amino acid transport.

Potential Commercial Applications

The potential commercial applications of this technology include:

  • Pharmaceutical companies developing new drugs targeting amino acid transport for cancer treatment.
  • Biotech companies exploring the use of amino acid transporter inhibitors in various therapeutic areas.

Possible Prior Art

One possible prior art in this field is the use of amino acid transporter inhibitors in research settings to study cell metabolism and growth. However, the specific compounds and applications disclosed in this patent application may represent novel advancements in the field.

Unanswered Questions

How do these compounds compare to existing amino acid transporter inhibitors in terms of efficacy and safety?

These compounds may offer advantages over existing inhibitors, but further research and clinical trials would be needed to determine their comparative efficacy and safety profiles.

What are the potential challenges in developing these compounds into viable treatments for cancer and other diseases?

Challenges may include optimizing the compounds for maximum effectiveness, navigating regulatory approval processes, and ensuring the compounds are well-tolerated in patients.


Original Abstract Submitted

The present disclosure provides compounds useful as amino acid transporter inhibitors. Amino acid transporter inhibitors are useful to treat a variety of diseases, disorders, or conditions including cancer.