Engineered Probiotic Delivery System for Anti-SARS-COV-2 Treatment and Immunity Against Viruses

Abstract: a novel genetically modified bacterium is disclosed. the bacterium has one or more anti-spike glycoprotein nanobodies on the outer membrane of the bacterium. in one embodiment, one or more of the anti-spike glycoprotein nanobodies have been fused with intimin. in another embodiment, one or more of the anti-spike glycoprotein nanobodies have been fused with lpp-ompa.

Inventor(s): Nitin S Kamble, Nalinikanth Kotagiri

CPC Classification: A61K39/0258 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

Search for rejections for patent application number 20250213666