Metal(loid)-Based Compositions and Uses Thereof Against Bacterial Biofilms

Abstract: described herein are new compositions comprising a combination of metal(loid)-based antimicrobials (mbas) that are effective against bacterial biofilms. in embodiments the composition comprises a combination of metal(loid) selected from: a) at least two metals; and b) at least one metal and at least one metalloid. examples of metal(s) and metalloid(s) useful in the combination include, silver nitrate, potassium tellurite, hydrogen tetrachloroaurate (iii), nickel sulfate, copper (ii) sulfate, aluminium sulfate, gallium nitrate, sodium selenite, and zinc sulfate. some combinations are broad-spectrum while others are especially effective against bacterial biofilms resulting from the growth of gram-negative bacteria or the growth of gram-positive bacteria. the compositions may be used in methods for disruption and/or of removal of biofilm present on a surface, or for coating purposes thereby providing anti-biofilm activity to a surface.

Inventor(s): Raymond J. Turner, Ali Pormohammad

CPC Classification: A01N59/16 (PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff ); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms ); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS)

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