20250154156. (Shenzhen Forward Pharmaceuticals Co., Limited)
QUINAZOLINE DERIVATIVE AS KRAS G12C MUTATION INHIBITOR
Abstract: provided are a quinazoline derivative of formula (ii) and a preparation method therefor, the quinazoline derivative being used as a kras g12c mutation inhibitor. the kras g12c mutation inhibitor can more efficiently inhibit kras g12c mutation, prevents drug-resistant mutation, and has good metabolic stability.
Inventor(s): Chaochun ZHANG, Xuan YANG, Kai GAO, Chenggang ZHU, Liming BAO, Chaole CHEN, Xiangyan MIN, Qianwen WANG, Chunniu WANG, Liangliang XU
CPC Classification: C07D487/04 (Ortho-condensed systems)
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Categories:
- Patent Applications
- Shenzhen Forward Pharmaceuticals Co., Limited
- CPC C07D487/04
- Chaochun ZHANG of Shenzhen, Guangdong CN
- Xuan YANG of Shenzhen, Guangdong CN
- Kai GAO of Shenzhen, Guangdong CN
- Chenggang ZHU of Shenzhen, Guangdong CN
- Liming BAO of Shenzhen, Guangdong CN
- Chaole CHEN of Shenzhen, Guangdong CN
- Xiangyan MIN of Shenzhen, Guangdong CN
- Qianwen WANG of Shenzhen, Guangdong CN
- Chunniu WANG of Shenzhen, Guangdong CN
- Liangliang XU of Shenzhen, Guangdong CN