18939874. DETERMINING WHETHER AN IBD PATIENT WILL RESPOND TO 5-ASA THERAPY (President and Fellows of Harvard College)
DETERMINING WHETHER AN IBD PATIENT WILL RESPOND TO 5-ASA THERAPY
Organization Name
President and Fellows of Harvard College
Inventor(s)
Raaj S. Mehta of Cambridge MA US
Curtis Huttenhower of Cambridge MA US
Andrew T. Chan of Cambridge MA US
Jared R. Mayers of Brookline MA US
Emily Balskus of Cambridge MA US
DETERMINING WHETHER AN IBD PATIENT WILL RESPOND TO 5-ASA THERAPY
This abstract first appeared for US patent application 18939874 titled 'DETERMINING WHETHER AN IBD PATIENT WILL RESPOND TO 5-ASA THERAPY
Original Abstract Submitted
The invention relates to a method of determining whether a patient diagnosed with inflammatory bowel disease (will respond to 5-ASA therapy which includes the steps of: obtaining a stool sample from the patient, analyzing the sample for the presence of microbial acetyltransferase genes capable of converting 5-ASA to the clinically ineffective N-acetyl 5-ASA, if microbial acetyltransferase genes are not present in the sample, the patient will respond to 5-ASA therapy and such therapy should be administered; if microbial acetyltransferase genes are present in the sample, the patient will not respond to 5-ASA therapy and a second line therapy should be administered.
(Ad) Transform your business with AI in minutes, not months
Trusted by 1,000+ companies worldwide
