18931785. ANTI-COAGULATING HYDROGEL NANOFILM FOR CELL ENCAPSULATION (Seoul National University R&DB Foundation)

ANTI-COAGULATING HYDROGEL NANOFILM FOR CELL ENCAPSULATION

Organization Name

Seoul National University R&DB Foundation

Inventor(s)

Nathaniel Suk-Yeon Hwang of Seoul KR

Young-sun Lee of Seoul KR

Kyoung-Ha So of Seoul KR

Dong-Hyun Lee of Seoul KR

Seh Ri Oh of Seoul KR

Suwan Jeon of Seoul KR

ANTI-COAGULATING HYDROGEL NANOFILM FOR CELL ENCAPSULATION

This abstract first appeared for US patent application 18931785 titled 'ANTI-COAGULATING HYDROGEL NANOFILM FOR CELL ENCAPSULATION

Original Abstract Submitted

The present invention relates to a method for modifying and cross-linking an anticoagulating hydrogel nanofilm for cell encapsulation. According to the present invention, the protection from the external environment and the control of material transfer can be improved due to the anticoagulant functionalization of the material surface. In addition, when applied into the body, it can prevent fibrosis, blood coagulation, protein adsorption, and platelet adhesion caused by immune responses, thereby preventing a decrease in cell viability caused by immune responses and improving cell survival rate.