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MICROSOFT TECHNOLOGY LICENSING, LLC (20250092082). PHOTON GENERATING SUBSTRATES FOR OLIGONUCLEOTIDE SYNTHESIS

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PHOTON GENERATING SUBSTRATES FOR OLIGONUCLEOTIDE SYNTHESIS

Organization Name

MICROSOFT TECHNOLOGY LICENSING, LLC

Inventor(s)

Bichlien Hoang Nguyen of Seattle WA US

Karin Strauss of Seattle WA US

Jake Allen Smith of Seattle WA US

Richard Prescott Rouse of Redmond WA US

Douglas Mitchell Carmean of Seattle WA US

Matthew David Turner of Carnation WA US

Gagan Gupta of Redmond WA US

PHOTON GENERATING SUBSTRATES FOR OLIGONUCLEOTIDE SYNTHESIS

This abstract first appeared for US patent application 20250092082 titled 'PHOTON GENERATING SUBSTRATES FOR OLIGONUCLEOTIDE SYNTHESIS

Original Abstract Submitted

photon generating substrates for light-directed oligonucleotide synthesis are disclosed. light is generated within a solid-state stack that supports growing oligonucleotides. the light may be generated by microleds, a pass-through liquid crystal panel, or an lcos system. light passes through a transmissive layer on which growing oligonucleotides are attached. patterning of the light is controlled by selective activation of the microleds or by selective control of the transparency of a liquid crystal layer. photolabile blocking groups are selectively removed by exposure to patterned light emitted from the photon generating substrate.

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