18736835. CAPTURING AND AMPLIFYING POLYNUCLEOTIDES, AND REUSING FLOWCELLS, USING SILICA PARTICLES (ILLUMINA, INC.)
Contents
CAPTURING AND AMPLIFYING POLYNUCLEOTIDES, AND REUSING FLOWCELLS, USING SILICA PARTICLES
Organization Name
Inventor(s)
Angelo La Rosa of Biggleswade (GB)
Xavier Von Hatten of Cambridge (GB)
CAPTURING AND AMPLIFYING POLYNUCLEOTIDES, AND REUSING FLOWCELLS, USING SILICA PARTICLES
This abstract first appeared for US patent application 18736835 titled 'CAPTURING AND AMPLIFYING POLYNUCLEOTIDES, AND REUSING FLOWCELLS, USING SILICA PARTICLES
Original Abstract Submitted
In some examples, a method of sequencing a polynucleotide includes hybridizing the polynucleotide to a first oligonucleotide coupled to a particle. The hybridized polynucleotide may be amplified using additional oligonucleotides coupled to the particle, to generate amplicons coupled to the particle. After the amplifying, the particle, having the amplicons coupled thereto, may be disposed within a flowcell. After disposing the particle within the flowcell, the particle may be dissolved, leaving the amplicons within the flowcell. The flowcell may be used to sequence the amplicons.
