18744136. TIS-L TARGETING ANTIVIRAL ANTISENSE OLIGONUCLEOTIDE WITH ABILITY TO INHIBIT VIRAL REPLICATION OF SARS-COV-2 (KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY)
Contents
TIS-L TARGETING ANTIVIRAL ANTISENSE OLIGONUCLEOTIDE WITH ABILITY TO INHIBIT VIRAL REPLICATION OF SARS-COV-2
Organization Name
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor(s)
Jeong-Sun Yang of Cheongju-si (KR)
Hansaem Lee of Cheongju-si (KR)
Joo-Yeon Lee of Cheongju-si (KR)
Kyung-Chang Kim of Cheongju-si (KR)
TIS-L TARGETING ANTIVIRAL ANTISENSE OLIGONUCLEOTIDE WITH ABILITY TO INHIBIT VIRAL REPLICATION OF SARS-COV-2
This abstract first appeared for US patent application 18744136 titled 'TIS-L TARGETING ANTIVIRAL ANTISENSE OLIGONUCLEOTIDE WITH ABILITY TO INHIBIT VIRAL REPLICATION OF SARS-COV-2
Original Abstract Submitted
The present disclosure relates to a TIS-L targeting antisense oligonucleotide that inhibits the viral replication of SARS-COV-2 and antiviral use thereof. Since the TIS-L targeting antisense oligonucleotide according to the present disclosure has a simple structure, it is easy to mass produce, and as it exhibits antiviral efficacy of 90% or more even at low doses against the original strain and various modified strains of the virus, it can be advantageously utilized in the development of COVID-19 treatment.
- KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Daehyun Baek of Seoul (KR)
- Hee Ryung Chang of Seoul (KR)
- Jeong-Sun Yang of Cheongju-si (KR)
- Hansaem Lee of Cheongju-si (KR)
- Man-Seong Park of Seoul (KR)
- Heedo Park of Seoul (KR)
- Yoon Ki Kim of Daejeon (KR)
- Jeeyoon Chang of Daejeon (KR)
- Joori Park of Seoul (KR)
- Joo-Yeon Lee of Cheongju-si (KR)
- Kyung-Chang Kim of Cheongju-si (KR)
- C12N15/113
- A61P31/14
- CPC C12N15/1131