18812424. METHODS OF ISOLATING ALLERGEN-SPECIFIC ANTIBODIES FROM HUMANS AND USES THEREOF (The Board of Trustees of the Leland Stanford Junior University)

METHODS OF ISOLATING ALLERGEN-SPECIFIC ANTIBODIES FROM HUMANS AND USES THEREOF

Organization Name

The Board of Trustees of the Leland Stanford Junior University

Inventor(s)

Derek Croote of San Francisco CA (US)

Stephen R. Quake of Stanford CA (US)

Kari Nadeau of Stanford CA (US)

Spyros Darmanis of San Francisco CA (US)

David N. Cornfield of Stanford CA (US)

METHODS OF ISOLATING ALLERGEN-SPECIFIC ANTIBODIES FROM HUMANS AND USES THEREOF

This abstract first appeared for US patent application 18812424 titled 'METHODS OF ISOLATING ALLERGEN-SPECIFIC ANTIBODIES FROM HUMANS AND USES THEREOF

Original Abstract Submitted

In one aspect, methods of generating human monoclonal antibodies that specifically binds to an allergen are provided. In some embodiments, the monoclonal antibodies are generated from sequences identified from isolated single B cells from a human subject who is allergic to the allergen.