18815119. NON-INVASIVE CLASSIFICATION OF BENIGN AND MALIGNANT MELANOCYTIC LESIONS USING MICRORNA PROFILING (THE REGENTS OF THE UNIVERSITY OF CALIFORNIA)
Contents
NON-INVASIVE CLASSIFICATION OF BENIGN AND MALIGNANT MELANOCYTIC LESIONS USING MICRORNA PROFILING
Organization Name
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor(s)
Robert Judson-torres of San Francisco CA (US)
Maria Wei of San Francisco CA (US)
NON-INVASIVE CLASSIFICATION OF BENIGN AND MALIGNANT MELANOCYTIC LESIONS USING MICRORNA PROFILING
This abstract first appeared for US patent application 18815119 titled 'NON-INVASIVE CLASSIFICATION OF BENIGN AND MALIGNANT MELANOCYTIC LESIONS USING MICRORNA PROFILING
Original Abstract Submitted
Differentiating benign cutaneous lesions from melanoma is an imprecise and subjective endeavor. The use of micro-RNAs has been investigated, but results have not been consistent across studies and clinical applications are lacking. The invention provides new micro-RNA signatures for differentiating benign lesions from melanoma. The micro-RNA signatures are robust, being stable across detection platforms, diverse sample types, and patient populations. The diagnostic methods based on these signatures control for variations in lesion composition and sample diversity, and permit cross-platform comparisons. The micro-RNA signatures and methods are amenable to the use of samples from convenient non-invasive tape strip biopsy.
