18694720. PROMOTING MYELINATION BY N-ACETYLGLUCOSAMINE AND MODULATION OF N-GLYCAN BRANCHING (THE REGENTS OF THE UNIVERSITY OF CALIFORNIA)
Contents
PROMOTING MYELINATION BY N-ACETYLGLUCOSAMINE AND MODULATION OF N-GLYCAN BRANCHING
Organization Name
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor(s)
Michael Demetriou of Irvine CA (US)
Alexander Brandt of Irvine CA (US)
PROMOTING MYELINATION BY N-ACETYLGLUCOSAMINE AND MODULATION OF N-GLYCAN BRANCHING
This abstract first appeared for US patent application 18694720 titled 'PROMOTING MYELINATION BY N-ACETYLGLUCOSAMINE AND MODULATION OF N-GLYCAN BRANCHING
Original Abstract Submitted
The present invention features compositions and methods for the repair of myelin and/or treatment of demyelinating diseases. The demyelinating disease may be multiple sclerosis (MS), optic neuritis, myelin oligodendrocyte glycoprotein antibody associated disease, neuromyelitis optica spectrum disorder, transverse myelitis, or acute disseminated encephalomyelitis. The compositions may include N-acetylglucosamine (GIcNAc), GlcNAc-6-acetate, or a combination thereof. The method may involve administering the compositions to a subject in need.
