18635082. METHOD OF GENERATING iPS CELL AND iPS CELL GENERATION SYSTEM simplified abstract (CANON KABUSHIKI KAISHA)
Contents
- 1 METHOD OF GENERATING iPS CELL AND iPS CELL GENERATION SYSTEM
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 METHOD OF GENERATING iPS CELL AND iPS CELL GENERATION SYSTEM - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Key Features and Innovation
- 1.6 Potential Applications
- 1.7 Problems Solved
- 1.8 Benefits
- 1.9 Commercial Applications
- 1.10 Questions about iPS Cell Generation
- 1.11 Original Abstract Submitted
METHOD OF GENERATING iPS CELL AND iPS CELL GENERATION SYSTEM
Organization Name
Inventor(s)
Katsuaki Deguchi of Otawara (JP)
METHOD OF GENERATING iPS CELL AND iPS CELL GENERATION SYSTEM - A simplified explanation of the abstract
This abstract first appeared for US patent application 18635082 titled 'METHOD OF GENERATING iPS CELL AND iPS CELL GENERATION SYSTEM
Simplified Explanation
The method described in the patent application involves extracting monocytes from mononuclear cells in the blood, reprogramming these monocytes to create iPS cells, and culturing the remaining cells to prepare raw material for iPS cell generation.
- Monocytes are extracted from mononuclear cells in the blood.
- The extracted monocytes are reprogrammed to generate iPS cells.
- The remaining cells are cultured to prepare raw material for iPS cell generation.
Key Features and Innovation
- Extraction of monocytes from mononuclear cells in the blood.
- Reprogramming of monocytes to create iPS cells.
- Culturing of remaining cells to prepare raw material for iPS cell generation.
Potential Applications
This technology could be used in regenerative medicine, drug discovery, and disease modeling.
Problems Solved
This technology addresses the need for a reliable method to generate iPS cells from monocytes.
Benefits
- Efficient generation of iPS cells.
- Potential for personalized medicine applications.
- Contribution to advancements in regenerative medicine.
Commercial Applications
- Regenerative medicine therapies.
- Pharmaceutical drug development.
- Research tools for disease modeling.
Questions about iPS Cell Generation
How can iPS cells be used in regenerative medicine?
iPS cells have the potential to differentiate into various cell types, making them valuable for regenerative medicine applications.
What are the challenges in reprogramming monocytes to generate iPS cells?
Reprogramming monocytes to iPS cells involves overcoming barriers such as epigenetic modifications and cell fate determination.
Original Abstract Submitted
According to one embodiment, a method of generating an iPS cell includes extracting monocytes from mononuclear cells separated from whole blood to separate the mononuclear cells into the monocytes and non-monocytes, reprogramming the separated monocytes to generate a monocyte-derived iPS cell, and culturing the separated non-monocytes in a first culture medium to prepare first raw material cells for iPS cell generation.