18604656. METHOD FOR DETECTING A PHAGE OR ANTIBIOTIC SENSITIVITY WITH RESPECT TO A BACTERIAL STRAIN simplified abstract (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE)
Contents
METHOD FOR DETECTING A PHAGE OR ANTIBIOTIC SENSITIVITY WITH RESPECT TO A BACTERIAL STRAIN
Organization Name
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventor(s)
Pierre Marcoux of Grenoble cedex (FR)
Emmanuel Picard of Grenoble cedex (FR)
Larry O’connell of Londres (GB)
METHOD FOR DETECTING A PHAGE OR ANTIBIOTIC SENSITIVITY WITH RESPECT TO A BACTERIAL STRAIN - A simplified explanation of the abstract
This abstract first appeared for US patent application 18604656 titled 'METHOD FOR DETECTING A PHAGE OR ANTIBIOTIC SENSITIVITY WITH RESPECT TO A BACTERIAL STRAIN
The abstract describes a method for detecting the lytic activity of phages or antibiotics on a bacterial strain using a multiwell plate and a transparent support.
- The method involves placing samples containing phages or antibiotics in wells of a multiwell plate.
- Bacteria from the bacterial strain are deposited on a transparent area of a support.
- The multiwell plate is then applied against the support so that each sample comes into contact with the bacteria deposit.
- The activity or absence of activity of the phage or antibiotic on the bacterial strain is determined for each well by analyzing light signals transmitted through the wells.
Potential Applications: - Research laboratories studying bacteriophages and antibiotics. - Pharmaceutical companies developing new antimicrobial treatments.
Problems Solved: - Efficiently testing the effectiveness of phages or antibiotics on specific bacterial strains. - Providing a standardized method for evaluating lytic activity.
Benefits: - Rapid screening of multiple samples. - Precise determination of phage or antibiotic activity.
Commercial Applications: Title: Rapid Antibiotic and Phage Sensitivity Testing Method This technology could be used in pharmaceutical research and development, clinical diagnostics, and biotechnology companies producing antimicrobial products.
Questions about the technology: 1. How does this method improve upon traditional antibiotic sensitivity testing? 2. What are the potential implications of this technology for personalized medicine?
Original Abstract Submitted
A method for detecting a lytic activity of one or more types of phages or of the activity of one or more antibiotics with respect to a bacterial strain, the method including using a first multiwell plate, each well receiving a sample containing phages or antibiotics, making at least one deposit on a transparent area of a support, the deposit containing bacteria of the bacterial strain, applying the first plate against the support so that each sample in each well comes into contact with the deposit, for each well, determining, using the detection means, the activity or absence of activity of the phage or antibiotic with respect to the bacterial strain, taking into account the intensity of light signals transmitted through each well and/or the variation thereof over time.
