18676514. CHIRAL AMINE-SQUARAMIDE COMPOUND BASED ON SPIROBIINDANE SKELETON, PREPARATION METHOD AND USE THEREOF simplified abstract (ZHEJIANG UNIVERSITY)
CHIRAL AMINE-SQUARAMIDE COMPOUND BASED ON SPIROBIINDANE SKELETON, PREPARATION METHOD AND USE THEREOF
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CHIRAL AMINE-SQUARAMIDE COMPOUND BASED ON SPIROBIINDANE SKELETON, PREPARATION METHOD AND USE THEREOF - A simplified explanation of the abstract
This abstract first appeared for US patent application 18676514 titled 'CHIRAL AMINE-SQUARAMIDE COMPOUND BASED ON SPIROBIINDANE SKELETON, PREPARATION METHOD AND USE THEREOF
The abstract describes a chiral amine-squaramide compound based on a spirobiindane skeleton, its preparation method, and its use in asymmetric catalytic organic reactions.
- The chiral amine-squaramide compound has the general formula (I) and exhibits good catalytic activity and enantioselectivity.
- It is obtained by adding a compound of formula (II) with squaric acid ester to prepare the compound of formula (I).
- The synthetic reaction route is simple and suitable for large-scale applications.
- The compound has economic utility and promising industrial applications.
Potential Applications: - Asymmetric catalytic organic reactions - Pharmaceutical industry for chiral drug synthesis - Chemical industry for enantioselective transformations
Problems Solved: - Enhances enantioselectivity in organic reactions - Provides a cost-effective and efficient catalyst for industrial applications
Benefits: - Improved efficiency in asymmetric catalysis - Cost-effective production process - Enhanced chiral selectivity in chemical reactions
Commercial Applications: - Production of chiral pharmaceuticals - Chemical manufacturing processes requiring enantioselective catalysts
Questions about the technology: 1. How does the chiral amine-squaramide compound improve enantioselectivity in organic reactions? 2. What are the potential industrial applications of this compound in the pharmaceutical and chemical industries?
Frequently Updated Research: - Ongoing studies on the optimization of the chiral amine-squaramide compound for specific organic transformations.
Original Abstract Submitted
A chiral amine-squaramide compound based on a spirobiindane skeleton, a preparation method and use thereof provided. The chiral amine-squaramide is an enantiomeric compound having the general formula (I) and is useful for asymmetric catalytic organic reactions with good catalytic activity and enantioselectivity. The chiral amine-squaramide compound is obtained by preparation of compound of formula (I) through addition of a compound of formula (II) with squaric acid ester. The synthetic reaction route is simple, and it is easy for large-scale application. The novel chiral amine-squaramide organocatalyst has economic utility and promising industrial applications.
