18414085. CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON SEPARATE POLYNUCLEOTIDES FOR METHYLATION DETECTION simplified abstract (ILLUMINA, INC.)
CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON SEPARATE POLYNUCLEOTIDES FOR METHYLATION DETECTION
Organization Name
Inventor(s)
Aathavan Karunakaran of San Diego CA (US)
Shagesh Sridharan of San Diego CA (US)
Jonathan Mark Boutell of Cambridge (GB)
Gery M. Vessere of San Diego CA (US)
CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON SEPARATE POLYNUCLEOTIDES FOR METHYLATION DETECTION - A simplified explanation of the abstract
This abstract first appeared for US patent application 18414085 titled 'CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON SEPARATE POLYNUCLEOTIDES FOR METHYLATION DETECTION
The invention relates to methods of detecting modified cytosines in nucleic acid sequences.
- Simplified Explanation:
This patent application discusses techniques for identifying modified cytosines in genetic material.
- Key Features and Innovation:
- Detection methods for modified cytosines in nucleic acid sequences - Potential for identifying epigenetic modifications - Enhances understanding of gene regulation mechanisms - Can be used in research on diseases influenced by epigenetic changes - Offers a new tool for studying genetic expression patterns
- Potential Applications:
- Research in epigenetics - Understanding gene regulation - Disease research related to epigenetic modifications - Drug development targeting epigenetic changes
- Problems Solved:
- Difficulty in detecting modified cytosines - Limited tools for studying epigenetic modifications - Challenges in understanding gene regulation mechanisms
- Benefits:
- Improved accuracy in identifying modified cytosines - Enhanced research capabilities in epigenetics - Potential for new discoveries in gene regulation - Better understanding of diseases influenced by epigenetic changes
- Commercial Applications:
- Biotechnology companies for research tools - Pharmaceutical companies for drug development - Academic institutions for genetic research
- Questions about Modified Cytosine Detection:
1. How can the detection of modified cytosines impact disease research? - The ability to identify modified cytosines can provide insights into diseases influenced by epigenetic changes, leading to potential new treatments.
2. What are the implications of improved detection methods for gene regulation studies? - Enhanced detection methods can help researchers better understand how genes are regulated, opening up new avenues for genetic research.
- Frequently Updated Research:
- Stay updated on advancements in epigenetic research related to modified cytosine detection to enhance understanding of gene regulation mechanisms and disease pathways.
Original Abstract Submitted
The invention relates to methods of detecting modified cytosines in nucleic acid sequences.
