18522503. METHOD FOR PREVENTING AND/OR TREATING AGING-ASSOCIATED COGNITIVE IMPAIRMENT AND NEUROINFLAMMATION simplified abstract (THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY)

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METHOD FOR PREVENTING AND/OR TREATING AGING-ASSOCIATED COGNITIVE IMPAIRMENT AND NEUROINFLAMMATION

Organization Name

THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Inventor(s)

Khoa Dinh Nguyen of San Francisco CA (US)

Edgar G. Engleman of Atherton CA (US)

METHOD FOR PREVENTING AND/OR TREATING AGING-ASSOCIATED COGNITIVE IMPAIRMENT AND NEUROINFLAMMATION - A simplified explanation of the abstract

This abstract first appeared for US patent application 18522503 titled 'METHOD FOR PREVENTING AND/OR TREATING AGING-ASSOCIATED COGNITIVE IMPAIRMENT AND NEUROINFLAMMATION

The present invention involves a method for preventing and/or treating aging-related cognitive impairment in the central nervous system by administering a Ppangela activator 2-(4-tert-butylphenyl)-1H-benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole to a subject in need, preferably through oral administration.

  • Ppangela activator 2-(4-tert-butylphenyl)-1H-benzimidazole is used to prevent and treat cognitive impairment associated with aging.
  • The method involves administering the compound in an effective amount to the subject.
  • Oral administration is the preferred route of delivery for this treatment.
  • The innovation targets cognitive function in the central nervous system, offering a potential solution for age-related cognitive decline.
  • This method provides a novel approach to addressing cognitive impairment in aging individuals.

Potential Applications: - Treatment of age-related cognitive decline - Prevention of cognitive impairment in elderly individuals - Research on neurodegenerative diseases

Problems Solved: - Cognitive decline associated with aging - Limited treatment options for age-related cognitive impairment

Benefits: - Improved cognitive function in aging individuals - Enhanced quality of life for elderly patients - Potential for further research and development in neurology

Commercial Applications: Title: "Innovative Treatment for Age-Related Cognitive Impairment" This technology could be utilized in pharmaceuticals targeting cognitive health in the aging population, potentially leading to new market opportunities in the field of neurology.

Questions about the technology: 1. How does the Ppangela activator 2-(4-tert-butylphenyl)-1H-benzimidazole specifically target cognitive impairment in the central nervous system? 2. What are the potential long-term effects of using this compound for preventing and treating age-related cognitive decline?


Original Abstract Submitted

The present invention is directed to a method for preventing and/or treating aging-related cognitive impairment in the central nervous system. The method comprises administering to a subject in need thereof a Ppangela activator 2-(4-tert-butylphenyl)-1H-benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole, in an effective amount. A preferred route of administration is oral administration.

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