Difference between revisions of "Merck Sharp & Dohme LLC patent applications published on July 25th, 2024"
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+ | '''Summary of the patent applications from Merck Sharp & Dohme LLC on July 25th, 2024''' | ||
+ | |||
+ | 1. **Summary**: | ||
+ | The recent patents filed by Merck Sharp & Dohme LLC introduce innovative technologies in the fields of enzyme engineering, cancer treatment, monoclonal antibodies, and chemical synthesis. These patents focus on enhancing transaminase enzymes for specific compound reduction, utilizing PD-1 receptor antagonists for personalized cancer therapy, developing monoclonal antibodies for RSV infections, and inhibiting the G12C mutant of the KRAS protein for cancer treatment. The organization's patents showcase advancements in biotechnology, pharmaceuticals, and precision medicine. | ||
+ | |||
+ | 2. **Key Points of Patents**: | ||
+ | * Transaminase enzymes with improved properties for reducing specific compounds. | ||
+ | * PD-1 receptor antagonists for personalized cancer therapy based on biomarker alterations. | ||
+ | * Monoclonal antibodies with high anti-RSV neutralizing titers for RSV infections. | ||
+ | * Compounds inhibiting the G12C mutant of the KRAS protein for cancer treatment. | ||
+ | |||
+ | 3. **Notable Applications**: | ||
+ | * Pharmaceutical industry for drug synthesis, chemical industry for manufacturing processes, and biotechnology for enzyme engineering. | ||
+ | * Personalized cancer treatment based on biomarker activity, targeted therapy for genetic alterations, and advancements in precision medicine for cancer care. | ||
+ | * Treatment of RSV infections, prevention in high-risk populations, and development of new immunotherapy agents. | ||
+ | * Potential for improved outcomes in cancer patients, enhanced protection in vulnerable populations, and new therapeutic interventions. | ||
+ | |||
+ | |||
+ | |||
+ | |||
==Patent applications for Merck Sharp & Dohme LLC on July 25th, 2024== | ==Patent applications for Merck Sharp & Dohme LLC on July 25th, 2024== | ||
Revision as of 05:13, 26 July 2024
Summary of the patent applications from Merck Sharp & Dohme LLC on July 25th, 2024
1. **Summary**: The recent patents filed by Merck Sharp & Dohme LLC introduce innovative technologies in the fields of enzyme engineering, cancer treatment, monoclonal antibodies, and chemical synthesis. These patents focus on enhancing transaminase enzymes for specific compound reduction, utilizing PD-1 receptor antagonists for personalized cancer therapy, developing monoclonal antibodies for RSV infections, and inhibiting the G12C mutant of the KRAS protein for cancer treatment. The organization's patents showcase advancements in biotechnology, pharmaceuticals, and precision medicine.
2. **Key Points of Patents**:
* Transaminase enzymes with improved properties for reducing specific compounds. * PD-1 receptor antagonists for personalized cancer therapy based on biomarker alterations. * Monoclonal antibodies with high anti-RSV neutralizing titers for RSV infections. * Compounds inhibiting the G12C mutant of the KRAS protein for cancer treatment.
3. **Notable Applications**:
* Pharmaceutical industry for drug synthesis, chemical industry for manufacturing processes, and biotechnology for enzyme engineering. * Personalized cancer treatment based on biomarker activity, targeted therapy for genetic alterations, and advancements in precision medicine for cancer care. * Treatment of RSV infections, prevention in high-risk populations, and development of new immunotherapy agents. * Potential for improved outcomes in cancer patients, enhanced protection in vulnerable populations, and new therapeutic interventions.
Contents
- 1 Patent applications for Merck Sharp & Dohme LLC on July 25th, 2024
- 1.1 ARYL 3-OXOPIPERAZINE CARBOXAMIDES AND HETEROARYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS (18557667)
- 1.2 IL4I1 INHIBITORS AND METHODS OF USE (18556196)
- 1.3 SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT (18557458)
- 1.4 ANTIBODY NEUTRALIZING HUMAN RESPIRATORY SYNCYTIAL VIRUS (18630437)
- 1.5 METHODS OF TREATMENT OF CANCER PATIENTS HAVING ALTERED SETD2 BIOMARKER WITH A PD-1 ANTAGONIST (18561331)
- 1.6 TRANSAMINASE ENZYMES FOR THE TRANSAMINATION OF (1S,5R)-6,8-DIOXABICYCLO[3.2.1]OCTAN-4-ONE ([[Merck Sharp & Dohme LLC (18563157). TRANSAMINASE ENZYMES FOR THE TRANSAMINATION OF (1S,5R)-6,8-DIOXABICYCLO[3.2.1]OCTAN-4-ONE simplified abstract|18563157]])
Patent applications for Merck Sharp & Dohme LLC on July 25th, 2024
ARYL 3-OXOPIPERAZINE CARBOXAMIDES AND HETEROARYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS (18557667)
Main Inventor
Ashok Arasappan
IL4I1 INHIBITORS AND METHODS OF USE (18556196)
Main Inventor
George Madalin GIAMBASU
SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT (18557458)
Main Inventor
Kazuaki SHIBATA
ANTIBODY NEUTRALIZING HUMAN RESPIRATORY SYNCYTIAL VIRUS (18630437)
Main Inventor
Kalpit A. Vora
METHODS OF TREATMENT OF CANCER PATIENTS HAVING ALTERED SETD2 BIOMARKER WITH A PD-1 ANTAGONIST (18561331)
Main Inventor
Razvan CRISTESCU
TRANSAMINASE ENZYMES FOR THE TRANSAMINATION OF (1S,5R)-6,8-DIOXABICYCLO[3.2.1]OCTAN-4-ONE ([[Merck Sharp & Dohme LLC (18563157). TRANSAMINASE ENZYMES FOR THE TRANSAMINATION OF (1S,5R)-6,8-DIOXABICYCLO[3.2.1]OCTAN-4-ONE simplified abstract|18563157]])
Main Inventor
Karla M. Camacho Soto