View source for UNM RAINFOREST INNOVATIONS (20240277678). METHOD FOR TREATING OBESITY, DIABETES, CARDIOVASCULAR AND KIDNEY DISEASES BY REGULATING GPR30/GPER ACTIVITY simplified abstract

=METHOD FOR TREATING OBESITY, DIABETES, CARDIOVASCULAR AND KIDNEY DISEASES BY REGULATING GPR30/GPER ACTIVITY=


==Organization Name==

[[:Category:UNM RAINFOREST INNOVATIONS|UNM RAINFOREST INNOVATIONS]]


[[Category:UNM RAINFOREST INNOVATIONS]]

==Inventor(s)==

[[:Category:Eric R. Prossnitz of Albuquerque NM (US)|Eric R. Prossnitz of Albuquerque NM (US)]][[Category:Eric R. Prossnitz of Albuquerque NM (US)]]

[[:Category:Geetanjali Sharma of Albuquerque NM (US)|Geetanjali Sharma of Albuquerque NM (US)]][[Category:Geetanjali Sharma of Albuquerque NM (US)]]

[[:Category:Matthias Barton of Zurich (CH)|Matthias Barton of Zurich (CH)]][[Category:Matthias Barton of Zurich (CH)]]

[[:Category:Matthias R. Meyer of Stallikon (CH)|Matthias R. Meyer of Stallikon (CH)]][[Category:Matthias R. Meyer of Stallikon (CH)]]

==METHOD FOR TREATING OBESITY, DIABETES, CARDIOVASCULAR AND KIDNEY DISEASES BY REGULATING GPR30/GPER ACTIVITY - A simplified explanation of the abstract==


This abstract first appeared for US patent application 20240277678 titled 'METHOD FOR TREATING OBESITY, DIABETES, CARDIOVASCULAR AND KIDNEY DISEASES BY REGULATING GPR30/GPER ACTIVITY

The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of NOX and NOX-associated reactive oxygen species (ROS).

* Compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes
* Compounds that can be used as agonists and/or antagonists of the estrogen receptor
* Modulation of the expression/upregulation of NOX and NOX-associated reactive oxygen species (ROS)
* Treatment of disease states and conditions resulting from excessive formation of reactive oxygen species
* Potential therapeutic applications in the fields of molecular biology and pharmacology

Potential Applications:
- Treatment of obesity and diabetes
- Management of disease states related to excessive reactive oxygen species
- Pharmacological interventions in molecular biology research

Problems Solved:
- Addressing obesity and diabetes through targeted modulation of GPR30/GPER
- Managing disease states associated with reactive oxygen species overproduction
- Providing novel therapeutic approaches in molecular biology and pharmacology

Benefits:
- Improved treatment options for obesity and diabetes
- Targeted interventions for diseases linked to reactive oxygen species
- Advancements in molecular biology and pharmacology research

Commercial Applications:
Title: Novel Compounds for Treating Obesity and Diabetes: Market Implications
Description: The technology offers potential commercial uses in pharmaceuticals for obesity and diabetes treatment, as well as in research for disease states related to reactive oxygen species.

Questions about the technology:
1. How do compounds modulating GPR30/GPER offer new treatment possibilities for obesity and diabetes?
2. What are the potential implications of targeting NOX and NOX-associated ROS in disease management?


==Original Abstract Submitted==

the current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of gpr30/gper for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). these compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ros).



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