View source for Dermatology Hospital, Southern Medical University (20240262871). FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF simplified abstract

=FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF=


==Organization Name==

[[:Category:Dermatology Hospital, Southern Medical University|Dermatology Hospital, Southern Medical University]]


[[Category:Dermatology Hospital, Southern Medical University]]

==Inventor(s)==

[[:Category:Wujian Ke of Guangzhou (CN)|Wujian Ke of Guangzhou (CN)]][[Category:Wujian Ke of Guangzhou (CN)]]

[[:Category:Xiaohui Zhang of Guangzhou (CN)|Xiaohui Zhang of Guangzhou (CN)]][[Category:Xiaohui Zhang of Guangzhou (CN)]]

[[:Category:Liuyuan Wang of Guangzhou (CN)|Liuyuan Wang of Guangzhou (CN)]][[Category:Liuyuan Wang of Guangzhou (CN)]]

[[:Category:Yujiao Wu of Guangzhou (CN)|Yujiao Wu of Guangzhou (CN)]][[Category:Yujiao Wu of Guangzhou (CN)]]

[[:Category:Xinying Leng of Guangzhou (CN)|Xinying Leng of Guangzhou (CN)]][[Category:Xinying Leng of Guangzhou (CN)]]

[[:Category:Sheng Ke of Guangzhou (CN)|Sheng Ke of Guangzhou (CN)]][[Category:Sheng Ke of Guangzhou (CN)]]

==FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF - A simplified explanation of the abstract==


This abstract first appeared for US patent application 20240262871 titled 'FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF

The disclosure provides a fusion protein for detecting neurosyphilis and a kit for the same purpose. It introduces a novel method of diagnosing neurosyphilis by detecting the Nichols Houston strain TP0136 antibody level.

* Using molecular biology gene cloning and expression technologies, a recombinant protein of the syphilis Nichols Houston strain TP0136 is produced.
* A luciferase immunoprecipitation method is established for detecting the Nichols Houston strain TP0136 antibody.
* A kit is assembled with high sensitivity and prediction accuracy, large detection throughput, simple operation, and easy popularization.

**Potential Applications:**
This technology can be used in medical diagnostics and research laboratories for the accurate detection of neurosyphilis.

**Problems Solved:**
This technology addresses the need for a more effective and reliable method of diagnosing neurosyphilis.

**Benefits:**
The fusion protein and kit offer high sensitivity, prediction accuracy, and ease of use, making them valuable tools in the diagnosis of neurosyphilis.

**Commercial Applications:**
"Neurosyphilis Detection Fusion Protein Kit" - This technology can be commercialized as a diagnostic kit for healthcare facilities and research institutions.

**Prior Art:**
Prior research on neurosyphilis diagnosis and detection methods can be found in medical journals and scientific databases.

**Frequently Updated Research:**
Stay updated on advancements in molecular biology techniques and diagnostic tools for neurosyphilis detection.

**Questions about Neurosyphilis Detection Fusion Protein:**
1. What are the potential implications of using this fusion protein in clinical settings?
2. How does this technology compare to existing methods of neurosyphilis diagnosis?


==Original Abstract Submitted==

a fusion protein for detecting neurosyphilis and a kit thereof are provided in this disclosure. it is unexpectedly found in this disclosure that detecting the nichols houston strain tp0136 antibody level for diagnosis of neurosyphilis makes up a blank of diagnosis and detection methods of the neurosyphilis. using molecular biology gene cloning and expression technologies, a syphilis nichols houston strain tp0136 recombinant protein is obtained, a luciferase immunoprecipitation method for detecting a nichols houston strain tp0136 antibody is established, and a kit is assembled. such a kit has such unexpected technical effects of high sensitivity and high prediction accuracy, and has advantages of large detection throughput, simple operation and easy popularization.



[[Category:C07K14/20]]
[[Category:C12N15/63]]
[[Category:C12Q1/689]]
[[Category:CPC_C07K14/20]]