View source for BEIJING INSTITUTE OF HEART, LUNG AND BLOOD VESSEL DISEASES (20240229045). APTAMER FOR SPECIFICALLY RECOGNIZING SOLUBLE ST2 PROTEIN AND APPLICATION OF THE SAME simplified abstract

=APTAMER FOR SPECIFICALLY RECOGNIZING SOLUBLE ST2 PROTEIN AND APPLICATION OF THE SAME=


==Organization Name==

[[:Category:BEIJING INSTITUTE OF HEART, LUNG AND BLOOD VESSEL DISEASES|BEIJING INSTITUTE OF HEART, LUNG AND BLOOD VESSEL DISEASES]]


[[Category:BEIJING INSTITUTE OF HEART, LUNG AND BLOOD VESSEL DISEASES]]

==Inventor(s)==

[[:Category:Jie Du of Beijing (CN)|Jie Du of Beijing (CN)]][[Category:Jie Du of Beijing (CN)]]

[[:Category:Yuan Wang of Beijing (CN)|Yuan Wang of Beijing (CN)]][[Category:Yuan Wang of Beijing (CN)]]

[[:Category:Fengjuan Li of Beijing (CN)|Fengjuan Li of Beijing (CN)]][[Category:Fengjuan Li of Beijing (CN)]]

[[:Category:Xin Tan of Beijing (CN)|Xin Tan of Beijing (CN)]][[Category:Xin Tan of Beijing (CN)]]

[[:Category:Xue Wang of Beijing (CN)|Xue Wang of Beijing (CN)]][[Category:Xue Wang of Beijing (CN)]]

==APTAMER FOR SPECIFICALLY RECOGNIZING SOLUBLE ST2 PROTEIN AND APPLICATION OF THE SAME - A simplified explanation of the abstract==


This abstract first appeared for US patent application 20240229045 titled 'APTAMER FOR SPECIFICALLY RECOGNIZING SOLUBLE ST2 PROTEIN AND APPLICATION OF THE SAME

'''Simplified Explanation''': This patent application describes a nucleic acid aptamer that specifically recognizes soluble ST2 protein, which can be used for the detection of ST2 protein and the preparation of biosensors, as well as for the diagnosis and prognosis of cardiovascular diseases.

* Nucleic acid aptamer specifically recognizing soluble ST2 protein
* Aptamer has high specificity, stability, convenient synthesis, and easy labeling of functional groups
* Can be used for detection of ST2 protein, preparation of biosensors, and diagnosis/prognosis of cardiovascular diseases

'''Potential Applications''': The technology can be applied in the fields of medical diagnostics, biosensors, and personalized medicine for cardiovascular diseases.

'''Problems Solved''': The technology addresses the need for a specific method to detect ST2 protein, which is crucial for diagnosing and monitoring cardiovascular diseases.

'''Benefits''': The technology offers a highly specific and stable method for detecting ST2 protein, which can improve the accuracy and efficiency of cardiovascular disease diagnosis and prognosis.

'''Commercial Applications''': "Nucleic Acid Aptamer for Specific Detection of Soluble ST2 Protein" can be utilized in medical diagnostics companies, research institutions, and healthcare facilities for cardiovascular disease management.

'''Questions about Nucleic Acid Aptamer for Specific Detection of Soluble ST2 Protein''':
1. How does the nucleic acid aptamer specifically recognize soluble ST2 protein?
2. What are the potential implications of using this technology in personalized medicine for cardiovascular diseases?


==Original Abstract Submitted==

a nucleic acid aptamer specifically recognizing soluble st2 protein and its application, belonging to the field of variation or genetic engineering, are described. the technical problem addressed includes how to specifically detect sst2 protein. in order to address this technical problem, nucleic acid aptamers of single-stranded dna with nucleotide sequences are shown in seq id no. 1-10, respectively. selex technology, combined with high-throughput sequencing technology and bioinformatics analysis, reduces the rounds of screening and obtains candidate nucleic acid aptamers, and further analyzes its affinity and specificity to obtain a nucleic acid aptamer that specifically recognizes sst2 protein. the nucleic acid aptamer has the characteristics of high specificity, high stability, convenient synthesis, and easy labeling of functional groups, and the like, and may be used for the detection of sst2 protein and the preparation of biosensors, diagnosis and prognosis of cardiovascular diseases and other products.



[[Category:C12N15/115]]
[[Category:A61K31/7088]]
[[Category:G01N33/68]]
[[Category:CPC_C12N15/115]]