View source for 20250215436. Antisense Nucleic Acid (Stichting Amsterdam UMC)

= Antisense Nucleic Acids for Use in the Treatment for KCNQ1 Mutation Carriers =

'''Abstract''':
the invention relates to isolated antisense molecule capable of inhibiting the expression of the kcnq1 gene in a mammalian cell, wherein said antisense molecule comprises an anti-sense nucleic acid strand which is substantially complementary to a target region of a transcript encoded by the kcnq1 gene, wherein said antisense nucleic acid strand is at least complementary to snp rs1057128, rs8234 or rs17215465 in said target region.

'''Inventor(s)''': [[:Category:Yigal-Martin Pinto of Utrecht  NL|Yigal-Martin Pinto]], [[:Category:Anke Johanna Marina Tijsen of Kockengen  NL|Anke Johanna Marina Tijsen]], [[:Category:Lucia Cocera Ortega of Utrecht  NL|Lucia Cocera Ortega]]

'''CPC Classification''': [[:Category:CPC_C12N15/1138|C12N15/1138]] ({against receptors or cell surface proteins})


[[Category:Patent Applications]]
[[Category:Stichting Amsterdam UMC]]
[[Category:CPC_C12N15/1138]]
[[Category:Yigal-Martin Pinto of Utrecht  NL]]
[[Category:Anke Johanna Marina Tijsen of Kockengen  NL]]
[[Category:Lucia Cocera Ortega of Utrecht  NL]]

[https://wikipatents.org/index.php?search=20250215436+rejection&title=Special%3ASearch&wprov=acrw1_-1 Search for rejections for patent application number 20250215436]


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