View source for 20250215084. Antigen Binding (Immatics Biotechnologies)

= ANTIGEN BINDING PROTEINS SPECIFICALLY BINDING MAGE-A =

'''Abstract''':
the present invention concerns antigen binding proteins specifically binding melanoma associated antigen a (mage-a) protein-derived antigens. the invention in particular provides antigen binding proteins which specifically bind to the mage-a antigenic peptide comprising or consisting of seq id no: 1 in a complex with a major histocombatibility (mhc) protein. the antigen binding proteins of the invention contain, in particular, the complementary determining regions (cdrs) of novel engineered t cell receptors (tcrs) that specifically bind to said mage-a peptide/mhc complex. the antigen binding proteins of the invention are of use for the diagnosis, treatment and prevention of mage-a expressing cancerous diseases. further provided are nucleic acids encoding the antigen binding proteins of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen binding proteins and pharmaceutical compositions comprising the antigen binding proteins of the invention.

'''Inventor(s)''': [[:Category:Meike HUTT of Tübingen  DE|Meike HUTT]], [[:Category:Felix UNVERDORBEN of Tübingen  DE|Felix UNVERDORBEN]], [[:Category:Sebastian BUNK of Tübingen  DE|Sebastian BUNK]], [[:Category:Dominik MAURER of Tübingen  DE|Dominik MAURER]], [[:Category:Martin HOFMANN of Tübingen  DE|Martin HOFMANN]], [[:Category:Gabriele PSZOLLA of Tübingen  DE|Gabriele PSZOLLA]], [[:Category:Sara YOUSEF of Tübingen  DE|Sara YOUSEF]], [[:Category:Claudia WAGNER of Tübingen  DE|Claudia WAGNER]], [[:Category:Frank SCHWOEBEL of Tübingen  DE|Frank SCHWOEBEL]], [[:Category:Heiko SCHUSTER of Tübingen  DE|Heiko SCHUSTER]]

'''CPC Classification''': [[:Category:CPC_C07K16/2809|C07K16/2809]] (PEPTIDES  (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))


[[Category:Patent Applications]]
[[Category:Immatics Biotechnologies GmbH]]
[[Category:CPC_C07K16/2809]]
[[Category:Meike HUTT of Tübingen  DE]]
[[Category:Felix UNVERDORBEN of Tübingen  DE]]
[[Category:Sebastian BUNK of Tübingen  DE]]
[[Category:Dominik MAURER of Tübingen  DE]]
[[Category:Martin HOFMANN of Tübingen  DE]]
[[Category:Gabriele PSZOLLA of Tübingen  DE]]
[[Category:Sara YOUSEF of Tübingen  DE]]
[[Category:Claudia WAGNER of Tübingen  DE]]
[[Category:Frank SCHWOEBEL of Tübingen  DE]]
[[Category:Heiko SCHUSTER of Tübingen  DE]]

[https://wikipatents.org/index.php?search=20250215084+rejection&title=Special%3ASearch&wprov=acrw1_-1 Search for rejections for patent application number 20250215084]


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