View source for 20240041011. INFECTIOUS DISEASE MOUSE MODELS simplified abstract (The Jackson Laboratory)

=INFECTIOUS DISEASE MOUSE MODELS=


==Organization Name==

[[:Category:The Jackson  Laboratory|The Jackson  Laboratory]]


[[Category:The Jackson  Laboratory]]

==Inventor(s)==

[[:Category:James Keck of Granite Bay (CA)|James Keck of Granite Bay (CA)]][[Category:James Keck of Granite Bay (CA)]]

==INFECTIOUS DISEASE MOUSE MODELS - A simplified explanation of the abstract==


This abstract first appeared for US patent application 20240041011 titled 'INFECTIOUS DISEASE MOUSE MODELS

==Simplified Explanation==

The abstract of the patent application describes immunodeficient mouse models that are engrafted with cells containing a pathogen entry moiety, specifically for assessing pathogenic infections, particularly respiratory viruses.

* The patent application describes immunodeficient mouse models.
* These models are engrafted with cells that have a pathogen entry moiety.
* The purpose of these models is to assess pathogenic infections, specifically respiratory viruses.

Potential Applications:
* Research and development of antiviral drugs and vaccines.
* Understanding the mechanisms of pathogenic infections and host immune responses.
* Testing the efficacy of various treatments and interventions for respiratory viral infections.

Problems Solved:
* Lack of suitable animal models for studying pathogenic infections, especially respiratory viruses.
* Difficulty in assessing the effectiveness of potential treatments and interventions.
* Limited understanding of the host immune response to respiratory viral infections.

Benefits:
* Improved understanding of pathogenic infections and host immune responses.
* Enhanced ability to develop effective antiviral drugs and vaccines.
* More accurate assessment of treatment efficacy and intervention strategies.


==Original Abstract Submitted==

provided herein are immnunodeficient mouse models engrafted with cells comprising a pathogen entry moiety, for example, for assessing pathogenic infection. the pathogen may be a virus, such as a respiratory virus.



[[Category:A01K67/027]]
[[Category:C12N5/071]]
[[Category:C12N5/09]]