View source for 20240027325. METHOD AND APPARATUS FOR FLOW-BASED, SINGLE-PARTICLE AND/OR SINGLE-MOLECULE ANALYSIS simplified abstract (University of Washington)

=METHOD AND APPARATUS FOR FLOW-BASED, SINGLE-PARTICLE AND/OR SINGLE-MOLECULE ANALYSIS=


==Organization Name==

[[:Category:University of Washington|University of Washington]]


[[Category:University of Washington]]

==Inventor(s)==

[[:Category:Daniel T. Chiu of Seattle WA (US)|Daniel T. Chiu of Seattle WA (US)]][[Category:Daniel T. Chiu of Seattle WA (US)]]

[[:Category:Yifei Jiang of Seattle WA (US)|Yifei Jiang of Seattle WA (US)]][[Category:Yifei Jiang of Seattle WA (US)]]

[[:Category:Mengxia Zhao of Seattle WA (US)|Mengxia Zhao of Seattle WA (US)]][[Category:Mengxia Zhao of Seattle WA (US)]]

[[:Category:Yuanhua Cheng of Seattle WA (US)|Yuanhua Cheng of Seattle WA (US)]][[Category:Yuanhua Cheng of Seattle WA (US)]]

==METHOD AND APPARATUS FOR FLOW-BASED, SINGLE-PARTICLE AND/OR SINGLE-MOLECULE ANALYSIS - A simplified explanation of the abstract==


This abstract first appeared for US patent application 20240027325 titled 'METHOD AND APPARATUS FOR FLOW-BASED, SINGLE-PARTICLE AND/OR SINGLE-MOLECULE ANALYSIS

==Simplified Explanation==

The patent application describes systems and methods for analyzing particles flowing in a channel. The channel is designed to flow a particle through a lumen, with an interrogation window allowing light to pass into and out of the lumen. The system includes a light engine with a first light source positioned to emit first excitation light onto a first portion of the channel in the interrogation window, and a second light source positioned to emit second excitation light onto a second portion of the channel in the interrogation window.

* The system includes an emission fiber bundle with a first and second emission optical fiber arranged in a bundle head.
* The first light source emits first excitation light onto a first portion of the channel, while the second light source emits second excitation light onto a separate second portion of the channel.
* The emission fiber bundle collects emitted light from the particles in the channel for analysis.

Potential applications of this technology:

* Particle analysis in medical diagnostics, such as blood cell counting or detecting pathogens.
* Environmental monitoring, such as analyzing pollutants or microorganisms in water samples.
* Industrial applications, such as analyzing particles in manufacturing processes or quality control.

Problems solved by this technology:

* Enables real-time analysis of particles flowing in a channel, providing valuable information for various applications.
* Allows for simultaneous analysis of different portions of the channel, increasing efficiency and accuracy.
* Provides a compact and integrated system for particle analysis.

Benefits of this technology:

* Faster and more efficient particle analysis compared to traditional methods.
* Real-time monitoring and analysis of particles in a flowing system.
* Compact and integrated design for easy implementation in various settings.
* Simultaneous analysis of multiple portions of the channel for improved accuracy.


==Original Abstract Submitted==

systems and methods for analyzing particles flowing in a channel are described. in an embodiment, the channel is configured to flow a particle through a lumen of the channel, the channel defining an interrogation window configured to allow light to pass into and out of the lumen; a light engine comprising: a first light source positioned to output first excitation light onto a first portion of the channel in the interrogation window; and a second light source positioned to output second excitation light onto a second portion of the channel in the interrogation window separate from the first portion. in an embodiment, the systems include an emission fiber bundle comprising a first emission optical fiber and a second emission optical fiber, wherein a proximal end of first emission optical fiber and second emission optical fiber are arranged in an emission fiber bundle head.



[[Category:G01N15/14]]