View source for 18469538. Cyclophanes for Live-Cell Imaging simplified abstract (Northwestern University)

=Cyclophanes for Live-Cell Imaging=


==Organization Name==

[[:Category:Northwestern University|Northwestern University]]


[[Category:Northwestern University]]

==Inventor(s)==

[[:Category:Indranil Roy of Chicago IL (US)|Indranil Roy of Chicago IL (US)]][[Category:Indranil Roy of Chicago IL (US)]]

[[:Category:James Fraser Stoddart of Evanston IL (US)|James Fraser Stoddart of Evanston IL (US)]][[Category:James Fraser Stoddart of Evanston IL (US)]]

==Cyclophanes for Live-Cell Imaging - A simplified explanation of the abstract==


This abstract first appeared for US patent application 18469538 titled 'Cyclophanes for Live-Cell Imaging

The patent application describes cyclophanes, compositions, and methods for live cell imaging. The cyclophanes consist of a chromophore, a first linker unit, a molecular strut, and a second linker unit in an ordered, cyclic arrangement. These compositions can be taken up by cells and are resistant to photobleaching during live-cell imaging.

* Cyclophanes with an ordered, cyclic arrangement of components for live cell imaging
* Compositions capable of being taken up by cells and resisting photobleaching under live-cell imaging conditions
* Methods for live cell imaging using the described cyclophanes and compositions

Potential Applications:
- Biomedical research for studying cellular processes
- Drug development for screening compounds in live cells
- Bioimaging for visualizing cellular structures and dynamics

Problems Solved:
- Photobleaching during live-cell imaging
- Difficulty in visualizing cellular processes in real-time

Benefits:
- Enhanced imaging quality in live cells
- Improved accuracy in studying cellular dynamics
- Facilitates drug discovery and development processes

Commercial Applications:
Title: Advanced Live Cell Imaging Technology for Biomedical Research and Drug Development
This technology can be used in pharmaceutical companies, research institutions, and academic laboratories for various applications such as drug screening, cellular imaging, and studying biological processes.

Questions about Live Cell Imaging Technology:
1. How does this technology improve the quality of live cell imaging?
   - This technology enhances imaging quality by using cyclophanes that resist photobleaching, allowing for clearer and more accurate visualization of cellular processes.
2. What are the potential implications of this technology in drug development?
   - This technology can streamline drug development processes by enabling researchers to screen compounds in live cells more effectively, leading to the discovery of new therapeutic agents.


==Original Abstract Submitted==

Described herein are cyclophanes, compositions, and methods for live cell imaging. The cyclophanes comprise an ordered, cyclic arrangement of a chromophore, a first linker unit, a molecular strut, and a second linker unit. The compositions are capable of being taking up by cells and resist photobleaching under live-cell imaging conditions.



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