US Patent Application 18295244. IMAGE-BASED CELL SORTING SYSTEMS AND METHODS simplified abstract

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IMAGE-BASED CELL SORTING SYSTEMS AND METHODS

Organization Name

The Regents of the University of California

Inventor(s)

Yu-Hwa Lo of San Diego CA (US)

Yuanyuan Han of San Diego CA (US)

Yi Gu of San Diego CA (US)

Ce Zhang of La Jolla CA (US)

IMAGE-BASED CELL SORTING SYSTEMS AND METHODS - A simplified explanation of the abstract

This abstract first appeared for US patent application 18295244 titled 'IMAGE-BASED CELL SORTING SYSTEMS AND METHODS

Simplified Explanation

- The patent application is about systems, devices, and methods for imaging and sorting particles in a flow system, specifically cells in a flow cytometer. - The system includes a device that allows particles to flow through a channel. - An imaging system captures image data of the particles as they flow through the channel. - A processing unit analyzes the image data to determine a property associated with each particle. - Based on sorting criteria related to particle properties, the processing unit generates a control command for sorting the particles. - An actuator is used to direct each particle into one of several output paths in real-time. - The innovation allows for real-time imaging and sorting of particles, particularly cells, in a flow system. - This technology can be used in flow cytometry applications for various purposes, such as cell analysis and sorting based on specific properties.


Original Abstract Submitted

Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time.