US Patent Application 18248252. TYPE I CRISPR-ASSOCIATED TRANSPOSASE SYSTEMS simplified abstract

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TYPE I CRISPR-ASSOCIATED TRANSPOSASE SYSTEMS

Organization Name

Massachusetts Institute of Technology

Inventor(s)

Feng Zhang of Cambridge MA (US)

Makoto Saito of Cambridge MA (US)

Jonathan Strecker of Cambridge MA (US)

TYPE I CRISPR-ASSOCIATED TRANSPOSASE SYSTEMS - A simplified explanation of the abstract

This abstract first appeared for US patent application 18248252 titled 'TYPE I CRISPR-ASSOCIATED TRANSPOSASE SYSTEMS

Simplified Explanation

- The patent application is about systems and methods for targeted gene modification, targeted insertion, perturbation of gene transcripts, and nucleic acid editing. - The novel nucleic acid targeting systems consist of components from transposases, components from a CRISPR-Cas system, and a transposable element. - The invention aims to provide a more efficient and precise way to modify genes, insert specific genetic material, disrupt gene transcripts, and edit nucleic acids. - The combination of transposases, CRISPR-Cas components, and transposable elements allows for targeted and controlled manipulation of genetic material. - The patent application does not provide a specific title for the invention.


Original Abstract Submitted

Systems and methods for targeted gene modification, targeted insertion, perturbation of gene transcripts, and nucleic acid editing. The novel nucleic acid targeting systems can comprise components of one or more transposases, one or more components of a CRISPR-Cas system, and a transposable element.