US Patent Application 18246456. METHOD FOR PREDICTING IMMUNOTHERAPY RESISTANCE simplified abstract

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METHOD FOR PREDICTING IMMUNOTHERAPY RESISTANCE

Organization Name

KONINKLIJKE PHILIPS N.V.


Inventor(s)

Anja Van De Stolpe of Eindhoven (NL)

Yvonne Jeanette Wilhelmina Rozendaal of Eindhoven (NL)

METHOD FOR PREDICTING IMMUNOTHERAPY RESISTANCE - A simplified explanation of the abstract

This abstract first appeared for US patent application 18246456 titled 'METHOD FOR PREDICTING IMMUNOTHERAPY RESISTANCE

Simplified Explanation

- The patent application describes a method for determining the immunosuppressive state of a subject with a tumor. - The method involves analyzing the activity of Notch cellular signaling pathways. - This analysis can help assess whether immune checkpoint inhibitors would be a suitable treatment option for the subject. - The patent application also includes information about kits and their uses related to the invention.


Original Abstract Submitted

The present invention relates to a method for determining the immunosuppressive state of a subject having a tumor by analyzing the Notch cellular signaling pathways activity. The method can be used in assessing whether immune checkpoint inhibitors are a suitable treatment option for the subject. The invention further relates kits and uses thereof.