US Patent Application 18028311. COMPOSITIONS AND METHODS FOR AMELIORATING MEDICAL CONDITIONS simplified abstract

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COMPOSITIONS AND METHODS FOR AMELIORATING MEDICAL CONDITIONS

Organization Name

The Regents of the University of California

Inventor(s)

Daniel L. Kaufman of Los Angeles CA (US)

Jide Tian of Los Angeles CA (US)

COMPOSITIONS AND METHODS FOR AMELIORATING MEDICAL CONDITIONS - A simplified explanation of the abstract

This abstract first appeared for US patent application 18028311 titled 'COMPOSITIONS AND METHODS FOR AMELIORATING MEDICAL CONDITIONS

Simplified Explanation

- The patent application proposes the use of GABA-receptor agonists, either alone or in combination with other compounds, to treat and prevent infections caused by bacteria, fungi, and viruses. - The combination of GABA-receptor agonists with positive PAMs, anti-inflammatory compounds, and antiviral treatments is suggested to enhance the effectiveness of the treatment. - The goal of the invention is to ameliorate infection-related medical conditions, including those caused by the coronavirus. - The use of GABA-receptor agonists is expected to inhibit viral replication, particularly in the case of coronaviruses. - The invention aims to treat and prevent respiratory virus-related medical conditions. - The modulation of dysregulated immune responses is also targeted by the proposed treatment approach.


Original Abstract Submitted

Use of GABA-receptor agonists, either alone or with one or more positive PAMs, anti-inflammatory compounds, and/or antiviral treatments, e.g., one that limits viral replication or impacts other viral functions, to ameliorate, treat, and/or prevent illness arising from infections, including bacterial, fungal, and/or viral infections, inpatients, including to: ameliorate infection-related medical conditions; ameliorate and/or prevent coronavirus-related medical conditions; inhibit viral replication; inhibit corona virus replication; ameliorate and/or treat coronavirus-induced medical conditions; ameliorate and/or prevent respiratory virus-related medical conditions; and ameliorate and/or modulate dysregulated immune responses.