US Patent Application 17736105. CONCENTRATION DETERMINATION METHOD simplified abstract
Contents
CONCENTRATION DETERMINATION METHOD
Organization Name
Taiwan Semiconductor Manufacturing Company, Ltd.
Inventor(s)
Tung-Tsun Chen of Hsinchu City (TW)
CONCENTRATION DETERMINATION METHOD - A simplified explanation of the abstract
This abstract first appeared for US patent application 17736105 titled 'CONCENTRATION DETERMINATION METHOD
Simplified Explanation
The patent application describes a method for determining the concentration of a target material in a sample fluid using a bio-sensing integrated circuit.
- Dilution: The sample fluid is diluted with a specific dilution factor to create multiple diluted samples.
- Bio-sensing integrated circuit: A specialized circuit is used for bio-sensing, which can detect the presence of the target material.
- Application: The diluted samples are applied to the bio-sensing circuit for analysis.
- Measurement: The bio-sensing process provides measurement values for each diluted sample.
- Comparison: The measurement values are compared with a threshold value to identify the largest dilution factor that still produces a measurement value above the threshold.
- Concentration calculation: The concentration of the target material is calculated based on the identified dilution factor and a limit of detection.
Original Abstract Submitted
A concentration determination method includes the following steps. A sample fluid having a target material therein is diluted with a 1dilution factor to an Ndilution factor to form a 1sample to an Nsample. A bio-sensing integrated circuit having a 1assay to an Nassay is provided. The 1sample to the Nsample are respectively applied to the 1assay to the Nassay. A bio-sensing process is performed on the 1sample to the Nsample to obtain a 1measurement value to an Nmeasurement value. The 1measurement value to the Nmeasurement value are compared with a threshold value to determine a threshold dilution factor, which corresponds to a largest dilution factor that has a measurement value higher than the threshold value. A concentration of the target material is calculated based on the threshold dilution factor and a limit of detection.
